Publication
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis
Related publications (34)
Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells
The behaviour of cells cultured within three-dimensional (3D) structures rather than onto two-dimensional (2D) culture plastic more closely reflects their in vivo responses. Consequently, 3D culture systems are becoming crucial scientific tools in cancer c ...
Elsevier2010Whole-cell bioprocessing of human fetal cells for tissue engineering of skin
Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri
Current restrictions for human cell-based therapies have been related to technological limitations with regards to cellular proliferation capacity (simple culture conditions), maintenance of differentiated phenotype for primary human cell culture and trans ...
2009Adverse Effects of Industrial Multiwalled Carbon Nanotubes on Human Pulmonary Cells
The aim of this study was to evaluate adverse effects of multiwalled carbon nanotubes (MWCNT), produced for industrial purposes, on the human epithelial cell line A549. MWCNT were dispersed in dipalmitoyl lecithin (DPL), a component of pulmonary surfactant ...
2009Chromosomal Number Aberrations and Transformation in Adult Mouse Retinal Stem Cells In Vitro
Freddy Radtke, Ivan Stamenkovic
Purpose. The potential of stem cells (SCs) as a source for cell-based therapy on a wide range of degenerative diseases and damaged tissues such as retinal degeneration has been recognized. Generation of a high number of retinal stem cells (RSCs) in vitro w ...
2009Wound healing gene-family expression differences between fetal and foreskin cells used for bioengineered skin substitutes
Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri
For tissue engineering, several cell types and tissues have been proposed as starting material. Allogenic skin products available for therapeutic usage are mostly developed with cell culture and with foreskin tissue of young individuals. Fetal skin cells o ...
2008A novel method of dynamic culture surface expansion improves mesenchymal stem cell proliferation and phenotype
Hicham Majd, Boris Hinz, Lara Buscemi Estefanell, Pierre Jean Arnould Wipff
Repeated passaging in conventional cell culture reduces pluripotency and proliferation capacity of human mesenchymal stem cells (MSC). We introduce an innovative cell culture method whereby the culture surface is dynamically enlarged during cell proliferat ...
2008Application of pulsed-magnetic field enhances non-viral gene delivery in primary cells from different origins
Heinrich Hofmann, Alke Fink, Benedikt Steitz
Primary cell lines are more difficult to transfect when compared to immortalized/transformed cell lines, and hence new techniques are required to enhance the transfection efficiency in these cells. We isolated and established primary cultures of synoviocyt ...
2008In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes
Paul Joseph Dyson, Gabor Laurenczy, Claudine Scolaro, Gianni Sava
The antitumor activity of the organometallic ruthenium(II)-arene complexes, RuCl2(eta(6)-arene)(PTA), (arene = p-cymene, toluene, benzene, benzo-15-crown-5, 1-ethylbenzene-2,3-dimethylimidazolium tetrafluoroborate, ethyl benzoate, hexamethylbenzene; PTA = ...
2005Engineered Streptomyces quorum-sensing components enable inducible siRNA-mediated translation control in mammalian cells and adjustable transcription control in mice
BACKGROUND: Recent advances in functional genomics, gene therapy, tissue engineering, drug discovery and biopharmaceuticals production have been fostered by precise small-molecule-mediated fine-tuning of desired transgenes. METHODS: Capitalizing on well-ev ...
2005Lentivector-mediated transfer of Bmi-1 and telomerase in muscle satellite cells yields a duchenne myoblast cell line with long-term genotypic and phenotypic stability
Conditionally immortalized human cells are valuable substrates for basic biologic studies, as well as for the production of specific proteins and for the creation of bioartificial organs. We previously demonstrated that the lentivector-mediated transductio ...
2003