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Human audiometric thresholds do not predict specific cellular damage in the inner ear

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Active Control mitigating the Ear Canal Occlusion Effect caused by Hearing Aids

Thomas Stefan Zurbrügg

The World Health Organization (WHO) estimates the prevalence of a disabling hearing loss to be above 5% world-wide 1. A treatment with a hearing aid - be it behind-the-ear (BTE), in-the-ear (ITE) or receiver-in-canal (RIC) - involves some degree of occlusi ...

EPFL2014

Two-photon microscopy of the mouse cochlea in situ for cellular diagnosis

Demetri Psaltis, Ye Pu, Chia-Lung Hsieh, Xin Yang

Sensorineural hearing loss is the most common type of hearing loss worldwide, yet the underlying cause is typically unknown because the inner ear cannot be biopsied today without destroying hearing, and intracochlear cells have not been imaged with resolut ...

Spie-Soc Photo-Optical Instrumentation Engineers2013

Perceptual Coding of High-Quality Digital Audio

Christof Faller, Karlheinz Brandenburg

This paper introduces high-quality audio coding using psychoacoustic models. This technology is now abundant, with gadgets named after a standard (mp3 players) and the ability to play high-quality audio from literally billions of devices. The usual paradig ...

Ieee-Inst Electrical Electronics Engineers Inc2013

Nowadays, hearing impaired people can be treated with a multitude of different devices and surgical interventions that are selected in function of the type and degree of hearing loss of the patient. These known therapies cover the major part of possible he ...

EPFL2011

Design of a Semi-Implantable Hearing Device for Direct Acoustic Cochlear Stimulation

Yves Perriard, Hans Bernhard

A new hearing therapy based on direct acoustic cochlear stimulation was developed for the treatment of severe to profound mixed hearing loss. The device efficacy was validated in an initial clinical trial with four patients. This semi-implantable investiga ...

Institute of Electrical and Electronics Engineers2011

Using Modality Replacement to Facilitate Communication between Visually and Hearing-Impaired People

Oya Aran

Using sign language, speech, and haptics as communication modalities, a virtual treasure-hunting game serves as an entertainment and educational tool for visually and hearing impaired users. In recent years, there has been an increasing interest in human-c ...

2011

Control of Exocytosis by Synaptotagmins and Otoferlin in Auditory Hair Cells

Ralf Schneggenburger

In pre-hearing mice, vesicle exocytosis at cochlear inner hair cell (IHC) ribbon synapses is triggered by spontaneous Ca2+ spikes. At the onset of hearing, IHC exocytosis is then exclusively driven by graded potentials, and is characterized by higher Ca2+ ...

Society for Neuroscience2010

The DIRAC AWEAR Audio-Visual Platform for Detection of Unexpected and Incongruent Events

Petr Motlicek, Hynek Hermansky, Barbara Caputo, Jie Luo

It is of prime importance in everyday human life to cope with and respond appropriately to events that are not foreseen by prior experience. Machines to a large extent lack the ability to respond appropriately to such inputs. An important class of unexpect ...

Idiap2010

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Aim: Treatment of sensorineural hearing loss could be advanced using novel drug carriers such as hyperbranched polylysine (HBPL) or lipid nanocapsules (LNCs). This study examined HBPL and LNCs for their cellular uptake and possible toxicity in vitro and in ...

Future Medicine2009

Rate-Constrained Collaborative Noise Reduction for Wireless Hearing Aids

Martin Vetterli, Olivier Roy

Hearing aids are electronic, battery-operated sensing devices which aim at compensating various kinds of hearing impairments. Recent advances in low-power electronics coupled with progresses made in digital signal processing offer the potential for substan ...

2009