Human audiometric thresholds do not predict specific cellular damage in the inner ear
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A new hearing therapy based on direct acoustic cochlear stimulation was developed for the treatment of severe to profound mixed hearing loss. The device efficacy was validated in an initial clinical trial with four patients. This semi-implantable investiga ...
Institute of Electrical and Electronics Engineers2011
Using sign language, speech, and haptics as communication modalities, a virtual treasure-hunting game serves as an entertainment and educational tool for visually and hearing impaired users. In recent years, there has been an increasing interest in human-c ...
It is of prime importance in everyday human life to cope with and respond appropriately to events that are not foreseen by prior experience. Machines to a large extent lack the ability to respond appropriately to such inputs. An important class of unexpect ...
In pre-hearing mice, vesicle exocytosis at cochlear inner hair cell (IHC) ribbon synapses is triggered by spontaneous Ca2+ spikes. At the onset of hearing, IHC exocytosis is then exclusively driven by graded potentials, and is characterized by higher Ca2+ ...
Aim: Treatment of sensorineural hearing loss could be advanced using novel drug carriers such as hyperbranched polylysine (HBPL) or lipid nanocapsules (LNCs). This study examined HBPL and LNCs for their cellular uptake and possible toxicity in vitro and in ...
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