Synthesis and Biological Response of Size-Specific, Monodisperse Drug–Silica Nanoconjugates
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Directed assembly of nano building blocks offers a versatile route to the creation of complex nanostructures with unique properties. Bottom-up directed assembly of nanoparticles have been considered as one of the best approaches to fabricate such functiona ...
In the past decades, polymeric nanoparticles have emerged as a most promising and viable technology platform for targeted and controlled drug delivery. As vehicles, ideal nanoparticles are obliged to possess high drug loading levels, deliver drug to the sp ...
BACKGROUND: Nanoparticle exposure in utero might not be a major concern yet, but it could become more important with the increasing application of nanomaterials in consumer and medical products. Several epidemiologic and invitro studies have shown that nan ...
Nat Inst of Environ Health Sciences / The National Institute of Environmental Health Sciences (NIEHS)2015
Over the past few years, engineered nanomaterials (ENMs) have penetrated nearly every sector of modern life and their broad-scale use is steadily and rapidly increasing. The (expected) elevated levels of ENMs in the environment raise concerns with regard t ...
Gd in silica: Noncovalent confinement of a monoaqua Gd chelate into biocompatible silica nanoparticles (NPs; see figure) by a sol-gel method affords a new example of nanosized contrast agents with very high per-Gd relaxivities. Such NPs provide a route to ...
Two luminescent terbium and europium lanthanide chelates were efficiently embedded into silica nanoparticles by using a reverse microemulsion process. The incorporation was achieved without covalent bonding between the lanthanide chelates and the silica ma ...
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to change the landscape of the diagnosis and therapy of many diseases. In the past several decades, the advancement in nanotechnology and material science has resulted in a ...
The use of solvent-free microfluidics to fine-tune the physical and chemical properties of chitosan nanoparticles for drug delivery is demonstrated. Nanoparticle self-assembly is driven by pH changes in a water environment, which increases biocompatibility ...
Signicant progress has been made to synthesis colloidal particles capable of controlling shape , dimensions and structures. These nanoparticles placement and integration on sur- faces is the main challenges of engineering approaches. Here, we investigate t ...
Nanoscience is a young and growing field of science. It encompasses a diversity of sub-fields such as nanotechnology and nano-medicine, all of them seeking to realize the promises of nanoscale physics. Nano means: “billionth” and conceptually all nano-like ...