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Privacy and Security in the Genomic Era

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Direct-to-consumer genetic testing makes it possible for everyone to learn their genome sequences. In order to contribute to medical research, a growing number of people publish their genomic data on the Web, sometimes under their real identities. However, ...

2014

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2014

In recent years, whole genome sequencing (WGS) evolved from a futuristic-sounding research project to an increasingly affordable technology for determining complete genome sequences of complex organisms, including humans. This prompts a wide range of revol ...

2013

High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum

Stewart Cole, Claudia Sala, Swapna Uplekar

The transcriptional regulator GlxR has been characterized as a global hub within the gene-regulatory network of Corynebacterium glutamicum. Chromatin immunoprecipitation with a specific anti-GlxR antibody and subsequent high-throughput sequencing (ChIP-seq ...

Soc General Microbiology2013

Recent advancements in DNA sequencing technologies, accompanied by parallel development of sophisticated computational methods, offer an unprecedented opportunity to explore and study the genetic material of many organisms. However, despite the tremendous ...

EPFL2013

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We propose privacy-enhancing technologies for medical tests and personalized medicine methods, which utilize patients’ genomic data. Focusing specifically on a typical disease-susceptibility test, we develop a new architecture (between the patient and the ...

2013

Personal Use of the Genomic Data: Privacy vs. Storage Cost

Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro

In this paper, we propose privacy-enhancing technologies for personal use of the genomic data and analyze the tradeoff between genomic privacy and storage cost of the genomes. First, we highlight the potential privacy threats on the genomic data. Then, foc ...

2013

Addressing the Concerns of the Lacks Family: Quantification of Kin Genomic Privacy

Jean-Pierre Hubaux, Mathias Jacques Jean-Marc Humbert, Amalio Telenti, Erman Ayday

The rapid progress in human-genome sequencing is leading to a high availability of genomic data. This data is notoriously very sensitive and stable in time. It is also highly correlated among relatives. A growing number of genomes are becoming accessible o ...

2013

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According to many scientists and clinicians, genomics is the "next big thing" in the field of medicine. On one hand, decreasing costs in genome sequencing has been paving the way to better preventive and personalized medicine. On the other hand, genomic da ...

2013

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In this paper, we propose privacy-enhancing technologies for medical tests and personalized medicine methods that use patients' genomic data. Focusing on genetic disease-susceptibility tests, we develop a new architecture (between the patient and the medic ...

2013