Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides

Endoscopy can be used to obtain high-resolution images at large depths in biological tissues. Usually endoscopic devices have a diameter ranging from 1 to few millimeters. Using digital phase conjugation, it is possible to adapt ultrathin multimode fibers to endoscopic purposes. Recently, we demonstrated that a 330 mu m diameter, water-filled silica capillary waveguide can guide high frequency ultrasound waves through a 3 cm thick fat layer, allowing optical resolution photoacoustic imaging. Here we demonstrate that using digital phase conjugation, the same water-filled capillary waveguide (3 cm long) can be used as an endoscopic probe to obtain both fluorescence and optical resolution photoacoustic imaging, with no optical or acoustic elements at the tip of the waveguide. We study the consequences of using digital phase conjugation combined with a capillary waveguide and we conclude with possible future improvements of our endoscopic approach.

Experimental and numerical investigation of two-dimensional photonic crystals for application in integrated optics

David Leuenberger

Two-dimensional (2D) photonic crystals (PhCs) at near-infrared wavelengths are promising candidates for novel integrated optics applications. The main focus being on 'all PhC' monolithically integrated optical circuits. Because of well established fabrication technologies particular emphasis is on 'quasi' 2D PhCs where a 2D lattice of air holes is etched through a planar step-index waveguide providing the optical confinement in the third dimension. This approach has been successfully demonstrated both in GaAs and InP-based systems. We have studied vertical low-index-contrast structures both in GaAs and InP. These structures suffer inherently from radiation losses that are strongly affected by the air hole depth and shape. A semi-analytical 'ε"-model' enables out-of-plane scattering to be described by an effective imaginary dielectric constant in the air-holes which can be used in 2D finite difference time domain (FDTD) calculations. The model, once validated by 3D FDTD, allows us to deduce from optical simple slab transmission measurements the structural parameters (e.g. size, depth and form of the hole). The experimental transmission spectra are obtained with the so-called 'internal light source technique' (ILS), which allows for quantitative normalised transmission measurements, thus eliminating the uncertainties due to the in-out coupling arising in alternative characterisation techniques, i.e. end-fire. The ILS technique proved to be a versatile method without stringent limits for assessing the fabrication parameters (air-filling factor and loss) but also proved to be suitable for testing building blocks. In this thesis different building blocks were fabricated in the GaAs system and analysed using diverse modeling techniques (e.g. plane wave expansion, FDTD and coupled mode theory). The first building block was used to study contra-directional coupling of the fundamental mode with higher-order modes in channel waveguides. It is an extension of the work on waveguides with symmetric periodic corrugation to the case of multi periodicity. We showed that by breaking the translational symmetry in these structures referred to as hybrid waveguides, the number of mini-stopbands is increased and not, as one could have expected, decreased. A second building block analysed to guide light around the corner, are cavity resonant bends (CRBs). As our analysis showd that CRBs work best with non-degenerate cavity modes, different low-symmetry order cavities were studied with differ coupling coefficients between cavity and waveguides. Unfortunately, the resulting peak transmission and overall performance was below our expectations. An important building block in integrated optics are directional couplers. They have a potential for applications such as 3dB-intensity splitting or channel add-drop filtering. To reduce the coupling length, transmission measurements of a series of coupler structures of different lengths were taken. In the case of two W3 waveguides separated by a single row, the coupling length proved to be very dependent on the hole diameter in the single row. For this case the experimentally determined coupling length, which has been validated by both PWE and FDTD simulations, was of the order of 350 periods which corresponds to an absolute length of about 80 μm, a value that is small for conventional optics, but rather large for the domain of PhC optics where due to the unusually high propagation losses the integrated circuit has to be kept small. This value could, however, be reduced by a factor of at least three when reducing the ratio between the barrier hole and the nominal hole radius to 0.5. Finally we studied the waveguides needed to connect the different building blocks. The standard solution are channel waveguides, line-defects obtained by omitting a number of rows of holes. An alternative approach are coupled cavity waveguides (CCWs). They not only offer the potential for waveguiding but may also be used for non-linear optics by exploiting the special dispersion properties of CCWs (e.g. low group-velocity). A tight-binding model has been set-up that describes the interaction between the neighbouring cavities and that allows one to deduce the dispersion properties of the chain from the single cavity field distribution.

EPFL2004

Towards new applications using capillary waveguides

Emmanuel André Henri Bossy, Salma Farahi, Christophe Moser, Demetri Psaltis, Nicolino Stasio

In this paper we demonstrate the enhancement of the sensing capabilities of glass capillaries. We exploit their properties as optical and acoustic waveguides to transform them potentially into high resolution minimally invasive endoscopic devices. We show two possible applications of silica capillary waveguides demonstrating fluorescence and optical-resolution photoacoustic imaging using a single 330 mu m-thick silica capillary. A nanosecond pulsed laser is focused and scanned in front of a capillary by digital phase conjugation through the silica annular ring of the capillary, used as an optical waveguide. We demonstrate optical-resolution photoacoustic images of a 30 mu m-thick nylon thread using the water-filled core of the same capillary as an acoustic waveguide, resulting in a fully passive endoscopic device. Moreover, fluorescence images of 1.5 mu m beads are obtained collecting the fluorescence signal through the optical waveguide. This kind of silica-capillary waveguide together with wavefront shaping techniques such as digital phase conjugation, paves the way to minimally invasive multi-modal endoscopy. (C) 2015 Optical Society of America

Optical Soc Amer2015

Étude expérimentale des propriétés optiques des cristaux photoniques bidimensionnels et de leur accordabillité

Barbara Wild

Photonic crystals are periodic dielectric structures, where the periodicity varies in one, two or three dimensions. Analogous to the periodic potential of electrons in semiconductors, the periodic variation of the dielectric constant influences the electromagnetic properties. The energy of the light is separated in bandgaps, energy ranges in which the propagation of the light is forbidden for certain directions and energies. These properties suggest that photonic crystals may be suitable for fabrication of the components needed for integrated optics. Since the fabrication of three dimensional photonic crystals is still limited by complex fabrication problems we have studied two dimensional photonic crystals. These photonic crystals can be fabricated by standard microelectronic technology. The photonic crystals studied in this thesis consist of GaAs and InP based low index vertical waveguides with a matrix of holes etched into it. The fabrication of photonic crystals with good optical properties is an important factor for photonic crystal devices in integrated optics. In the first part we studied the optical properties of photonic crystal slabs and of Fabry-Pérot cavities. These structures were measured by the internal light source technique, which allows quantitative normalized transmission measurements. The photonic crystals were etched by three different dry etching technologies. Out-of plane scattering is described by a 2D-FDTD fit of the transmission spectra and by a semi-analytical model. The finite hole depth and the conical shape of the holes are important structural parameters. The detailed study of their effects yields an important feedback for the critical parameters of the fabrication process. Photonic crystal waveguides are another group of components in integrated optics. We measured two types of straight photonic crystal waveguides by the endfire technique. Here the light is coupled by optical fibers and ridge waveguides in the photonic crystal waveguides. The transmission spectra reveal fringes which are due to multiple interference of the light in the sample. This interference contains information about propagation losses of the waveguides and an analysis based on the Fourier transform of the transmission spectra enabled us to deduce the propagation losses of the photonic crystal waveguides. The necessity of tuning or trimming the optical properties of photonic crystals is an important issue either compensating fabrication imperfections (trimming) or controlling the optical properties on demand (tuning) for devices like filters. We have shown that it is possible to tune the optical properties of planar photonic crystal cavities by temperature. The experimental results were validated by theoretical calculations. Also we have shown that is possible to tune the optical properties of photonic crystals by infiltrating liquid crystals in the holes. Liquid crystals are a birefringent material whose optical axis can be tuned by external fields (electric, temperature, photonic source, etc.). Phase transitions exhibiting abrupt changes in the refractive index are important characteristics of liquid crystals. The holes of the photonic crystal are infiltrated by a reversible and reliable infiltration process. The infiltration efficiency and the orientation of the molecules in the holes were determined by polarization resolved internal light source measurements. We have shown that the frequency of the Fabry-Pérot resonance changes at the phase transitions of the liquid crystal.