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Physiological Adaptations to Sugar Intake: New Paradigms from Drosophila melanogaster

Related publications (36)

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Thermodynamics-based Metabolite Sensitivity Analysis in metabolic networks

Vassily Hatzimanikatis

The increasing availability of large metabolomics datasets enhances the need for computational methodologies that can organize the data in a way that can lead to the inference of meaningful relationships. Knowledge of the metabolic state of a cell and how ...

Elsevier2017

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Advances in medicine and biotechnology rely on the further understanding of biological processes. Despite the technological advances and increasing available types and amounts of omics data, significant biochemical knowledge gaps remain uncharacterised. We ...

2017

A review of sustainable energy access and technologies for healthcare facilities in the Global South

Silvia Hostettler, Andrea Franco, Marjan Shaker, Dikolela Kalubi

Access to reliable, affordable and sustainable energy is essential for improving living standards, development and economic growth. From a healthcare perspective, energy is a critical parameter for delivering and improving healthcare services and life-savi ...

Elsevier Science Bv2017

Sustainability assessment of succinic acid production technologies from biomass using metabolic engineering

Vassily Hatzimanikatis, Meriç Ataman, Merten Morales, Konrad Hungerbühler

Over the past few years, bio-succinic acid from renewable resources has gained increasing attention as a potential bio-derived platform chemical for the detergent/surfactant, ion chelator, food and pharmaceutical markets. Until now, much research was under ...

Royal Soc Chemistry2016

Navigating and Managing the Complexity of Genome Scale Metabolic Networks for Studies in Cellular Physiology and Industrial Biotechnology

Meriç Ataman

Metabolism is a network of biochemical reactions that converts carbon sources to cellu-lar fuels and building blocks. Metabolism of many organisms has been studied for many decades. These studies define metabolism as a very large and complex network. Stoic ...

EPFL2016

Direct noninvasive estimation of myocardial tricarboxylic acid cycle flux in vivo using hyperpolarized 13C magnetic resonance

Rolf Gruetter, Hongxia Lei, Tian Cheng, Arnaud Comment, Josefina Adriana Maria Bastiaansen

BACKGROUND: The heart relies on continuous energy production and imbalances herein impair cardiac function directly. The tricarboxylic acid (TCA) cycle is the primary means of energy generation in the healthy myocardium, but direct noninvasive quantificati ...

Elsevier2015

Energy needs at the global level are gigantic and steadily increasing while the need to reduce carbon emissions is vital if catastrophic climate change is to be avoided. In the Global South, a large part of the population still lacks access to energy, whic ...

Springer International Publishing2015

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Resting skeletal muscle has a preference for the oxidation of lipids compared to carbohydrates and a shift towards carbohydrate oxidation is observed with increasing exercise. Lactate is not only an end product in skeletal muscle but also an important meta ...

2014

The cyclic AMP-dependent transcriptional regulator GlxR from Corynebacterium glutamicum is a member of the super-family of CRP/FNR (cyclic AMP receptor protein/fumarate and nitrate reduction regulator) transcriptional regulators that play central roles in ...

Public Library of Science2014

Elucidating the role of neuron-astrocyte metabolic coupling in learning and memory

Monika Tadi

The brain has very high energy demands that are mainly met by the circulating blood glucose to ensure its proper functioning. Thus, it is not surprising that though the human brain weighs only 2- 3% of the body weight, it consumes approximately 25% of tota ...

EPFL2013