Publication
The present invention relates to an agent or composition comprising at least one of: (i) a micro-RNA targeting a mitophagy-associated gene or a variant thereof, (ii) a vector comprising a nucleic acid encoding said micro-RNA or variant thereof, (iii) an inducer of said micro-RNA, and (iv) an inhibitor of said micro-RNA, for use as a medicament. In particular, the invention relates to substances and compositions useful in the treatment of mitochondria-related diseases, in a subject, or to enhance protocols of in vitro production of red blood cells.
Mats Julius Stensrud, Aaron Leor Sarvet
Christof Holliger, Aline Sondra Adler, Laetitia Janine Andrée Cardona, Jaspreet Singh Saini, Pilar Natalia Rodilla Ramírez, Ruizhe Pei