AnamniotesThe anamniotes are an informal group of craniates comprising all fishes and amphibians, which lay their eggs in aquatic environments. They are distinguished from the amniotes (reptiles, birds and mammals), which can reproduce on dry land either by laying shelled eggs or by carrying fertilized eggs within the female. Older sources, particularly before the 20th century, may refer to anamniotes as "lower vertebrates" and amniotes as "higher vertebrates", based on the antiquated idea of the evolutionary great chain of being.
BirdBirds are a group of warm-blooded vertebrates constituting the class Aves (ˈeɪviːz), characterised by feathers, toothless beaked jaws, the laying of hard-shelled eggs, a high metabolic rate, a four-chambered heart, and a strong yet lightweight skeleton. Birds live worldwide and range in size from the bee hummingbird to the common ostrich. There are about ten thousand living species, more than half of which are passerine, or "perching" birds.
AgnathaAgnatha ('ægnəθə,_æg'neɪθə; ) is an infraphylum of jawless fish in the phylum Chordata, subphylum Vertebrata, consisting of both present (cyclostomes) and extinct (conodonts and ostracoderms) species. Among recent animals, cyclostomes are sister to all vertebrates with jaws, known as gnathostomes. Recent molecular data, both from rRNA and from mtDNA as well as embryological data, strongly supports the hypothesis that living agnathans, the cyclostomes, are monophyletic.
Floor plateThe floor plate is a structure integral to the developing nervous system of vertebrate organisms. Located on the ventral midline of the embryonic neural tube, the floor plate is a specialized glial structure that spans the anteroposterior axis from the midbrain to the tail regions. It has been shown that the floor plate is conserved among vertebrates, such as zebrafish and mice, with homologous structures in invertebrates such as the fruit fly Drosophila and the nematode C. elegans.
Noggin (protein)Noggin, also known as NOG, is a protein that is involved in the development of many body tissues, including nerve tissue, muscles, and bones. In humans, noggin is encoded by the NOG gene. The amino acid sequence of human noggin is highly homologous to that of rat, mouse, and Xenopus (an aquatic frog genus). Noggin is an inhibitor of several bone morphogenetic proteins (BMPs): it inhibits at least BMP2, 4, 5, 6, 7, 13, and 14.
French flag modelThe French flag model is a conceptual definition of a morphogen, described by Lewis Wolpert in the 1960s. A morphogen is defined as a signaling molecule that acts directly on cells (not through serial induction) to produce specific cellular responses dependent on morphogen concentration. During early development, morphogen gradients generate different cell types in distinct spatial order. French flag patterning is often found in combination with others: vertebrate limb development is one of the many phenotypes exhibiting French flag patterning overlapped with a complementary pattern (in this case Turing pattern).
