Rapid Production of Submicron Drug Substance Particles by Supersonic Spray Drying
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Breast cancer is the most diagnosed malignancy in women worldwide, making effective prevention strategies crucial. Hormonal contraceptives, consisting of a synthetic progesterone receptor agonist alone or in combination with an estrogen, are used by millio ...
Motivated by improving the performance of particle-based Monte-Carlo simulations in the transitional regime, Fokker–Planck kinetic models have been devised and studied as approximations of the Boltzmann collision operator. By generalizing the linear drift ...
In recent years, considerable interest has been devoted to the interactions between cavitation bubbles and tissue-mimicking materials due to their promising applications in medicine and biomedical sciences. The strong fluid-structure interaction between a ...
AIP Publishing2023
The mechanism responsible for the production of energetic ions in the plume of hollow cathodes for electric propulsion is still an open issue. These ions are of concern to cathode and thruster lifetime, particularly for cathodes operating at high (>20 A) d ...
Using the Lambert function, Guittienne et al. [Phys. Plasmas 25, 093519 (2018)] derived two-fluid solutions for radial Langmuir probes in collisionless and isothermal plasma. In this Brief Communication, we point out the close analogy with classical compre ...
Amorphous solid dispersion (ASD) is one of the most promising enabling formulations featuring significant water solubility and bioavailability enhancements for biopharmaceutical classification system (BCS) class II and IV drugs. An accurate thermodynamic u ...
Highly loaded impellers, typically used in turbocharger and gas turbine applications, exhaust an unsteady, transonic flow that is nonuniform across the span and pitch and swirling at angles approaching tangential. With the exception of the flow angle, conf ...
Vortex breakdown of swirling, round jet flows is investigated in the compressible, subsonic regime by means of Direct Numerical Simulation (DNS). This is achieved by solving the compressible Navier-Stokes equations on a cylindrical grid using high-order sp ...
Highly-loaded impellers, typically used in turbocharger and gas turbine applications, exhaust an unsteady, transonic flow that is non-uniform across the span and pitch and swirling at angles approaching tangential. With the exception of the flow angle, con ...
In this work we apply the Continuation Multi-Level Monte Carlo (C-MLMC) algorithm proposed in Collier et al. (2014) to efficiently propagate operating and geometric uncertainties in inviscid compressible aerodynamics numerical simulations. The key idea of ...