Two sides of the same coin: A population genetics perspective on lethal mutagenesis and mutational meltdown
Graph Chatbot
Chat with Graph Search
Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.
DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.
We developed used a WebGIS platform prototype (GenMon) based on open source software (PostgreSQL, PostGIS, OpenLayers, Geoserver), to assess pedigree information, geographical concentration, socio-economic and environmental information. GenMon includes Pop ...
Beneficial mutations can co-occur when population structure slows down adaptation. Here, we consider the process of adaptation in asexual populations distributed over several locations ("islands"). New beneficial mutations arise at constant rate u(b), and ...
Identifying adaptively important loci in recently bottlenecked populations - be it natural selection acting on a population following the colonization of novel habitats in the wild, or artificial selection during the domestication of a breed - remains a ma ...
Fluctuations in ammonium (NH4+), measured as NH4-N loads using an ion-selective electrode installed at the inlet of a sewage treatment plant, showed a distinctive pattern which was associated to weekly (i.e., commuters) and seasonal (i.e., holidays) fluctu ...
We study the potential of a population of thermostatically controlled loads to track desired power signals with provable guarantees. Based on connecting the temperature state of an individual device with its internal energy, we derive necessary conditions ...
Consider a set of probes, called “agents”, who sample, based on opportunistic contacts, a population moving between a set of discrete locations. An example of such agents are Bluetooth probes that sample the visible Bluetooth devices in a population. Based ...
Taylor's law (TL) states that the variance V of a nonnegative random variable is a power function of its mean M; i.e., V = aM(b). TL has been verified extensively in ecology, where it applies to population abundance, physics, and other natural sciences. It ...
This paper presents a new mechanism for a better exploitation of surrogate models in the framework of Evolution Strategies (ESs). This mechanism is instantiated here on the self-adaptive surrogate-assisted Covariance Matrix Adaptation Evolution Strategy (( ...
It remains a central problem in population genetics to infer the past action of natural selection, and these inferences pose a challenge because demographic events will also substantially affect patterns of polymorphism and divergence. Thus it is imperativ ...
This article is concerned with the evolution of haploid organisms that reproduce asexually. In a seminal piece of work, Eigen and coauthors proposed the quasispecies model in an attempt to understand such an evolutionary process. Their work has impacted an ...
