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Soft Electrochemical Probes for Mapping the Distribution of Biomarkers and Injected Nanomaterials in Animal and Human Tissues

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Compact lensless digital holography

Manon Rostykus

Microscopy is of high interest for biology since it allows imaging features that are too small to be seen with naked eyes. However, cells are mostly transparent to visible and infrared light which makes it difficult to see with a traditional microscope. To ...

EPFL2018

Electrochemical Imaging of Cells and Tissues

Hubert Girault, Andreas Stephan Lesch, Tzu-En Lin

The technological and experimental progress in electrochemical imaging of biological specimens is discussed with a view on potential applications for skin cancer diagnostics, reproductive medicine and microbial testing. The electrochemical analysis of sing ...

2018

AFM contribution to unveil pro- and eukaryotic cell mechanical properties

Giovanni Dietler, Sandor Kasas, Petar Stupar

Atomic force microscopy is nowadays a well-established technique that permits the investigation of numerous parameters of living matter. In particular, it allows the exploration of the mechanical properties of living organisms in almost physiological condi ...

Elsevier2018

Structural and functional imaging of cells, tissues and organisms is crucial for understanding biomedical processes. Fluorescence microscopy is an established tool and has contributed to many discoveries in the life sciences. This technique provides molecu ...

EPFL2017

Fermi surface map of large-scale single-orientation graphene on SiO2

Huanyao Cun

Large scale tetraoctylammonium-assisted electrochemical transfer of graphene grown on single-crystalline Ir(1 1 1) films by chemical vapour deposition is reported. The transferred samples are characterized in air with optical microscopy, Raman spectroscopy ...

2017

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We present soft spider array for gentle contact mode scanning electrochemical microscopy (SECM) imaging of tissues. The spider array contains up to eight completely individual, parallel, and flexible carbon microelectrodes designed to scan square centimete ...

Electrochemical Society2017

Correlating microscopy techniques and ToF-SIMS analysis of fully grown mammalian oocytes

Sami Rtimi

The 2D-molecular thin film analysis protocol for fully grown mice oocytes is described using an innovative approach. Time-of-flight secondary ion mass spectrometry (ToF-SIMS), scanning electron microscopy (SEM), atomic force microscopy (AFM) and optical mi ...

Royal Soc Chemistry2016

Recent advances in optical microscopy enable the visualization and quantification of biol. processes within live cells. To a great extent, these imaging techniques remain limited by the phys. properties of the chem. probes that are used as fluorescent tags ...

2016

Giant apparent lattice distortions in STM images of corrugated sp2-hybridised monolayers

Alfredo Pasquarello, Harald Brune, François Patthey, Stefano Rusponi, Markus Etzkorn, Donat Fabian Natterer, Anne Lehnert, Quentin Dubout, Laurent Claude

We report on the strengths and limitations of scanning tunnelling microscopy (STM) when used for characterising atomic-scale features of quasi two-dimensional materials, such as graphene and single layers of hexagonal boron nitride, which may present stron ...

Institute of Physics (IoP) and Deutsche Physikalische Gesellschaft2016

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Although tremendous progress has been made in the diagnosis of melanoma, the identification of different stages of malignancy in a reliable way remains challenging. Current strategies rely on optical monitoring of the concentration and spatial distribution ...

Wiley-Blackwell2016