Abnormal creatine transport of mutations in monocarboxylate transporter 12 (MCT12) found in patients with age-related cataract can be partially rescued by exogenous chaperone CD147
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Lipophilicity of compounds with therapeutic interest represents one of the most important physicochemical parameters in predicting and interpreting transport processes across biological barriers. This property is commonly measured as a drug | membrane part ...
The aims of the preliminary study reported in this document were twofold. Firstly, within the context of the application of UHPFRC for the rehabilitation of reinforced concrete structures, to identify the phenomena that require further study with respect t ...
Proteins exist in one of two generally incompatible states: either membrane associated or soluble. Pore-forming proteins are exceptional because they are synthesized as a water-soluble molecule but end up being located in the membrane -- that is, they are ...
A review. This research group is working towards understanding the fundamental physicochem. mechanisms of trace metal biouptake by aquatic microorganisms in natural systems. Research is currently focused on identifying under what conditions uptake fluxes a ...
The invention relates to a measuring device which permits a very simple positioning of cells and vesicles respective of cell membranes on planar carriers. The invention also relates to a corresponding highly efficient method for the positioning and electri ...
Life cycle assessment (LCA) is a framework for comparing products according to their total estimated environmental impact, summed over all chemical emissions and activities associated with a product at all stages in its life cycle (from raw material acquis ...
Objectives: Intravesical BCG therapy remains the first-line prophylactic treatment for recurrences of superficial bladder tumours. However necessary the safety, of this medicinal product, for which a potential risk of complications was demonstrated during ...
Tumor necrosis factor TNF can trigger increases in membrane conductance of mammalian cells in a receptor-independent manner via its lectin-like domain. A lectin-deficient TNF mutant, lacking this activity, was able to bind to artificial liposomes in a pH-d ...
High stride-to stride variability and the inability to walk and talk at the same time have been associated with an increased risk of falling (1;2). The aim of this study was to compare stride-to-stride variation in stride length and velocity beween communi ...