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CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy

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CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy

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Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis

Multi-resistance of human enterovirus to UV-C disinfection and mutagenic nucleoside analogs

A Balance between Inhibitor Binding and Substrate Processing Confers Influenza Drug Resistance

Joint mouse-human phenome-wide association to test gene function and disease risk

Genetic, structural and phenotypic properties of MS2 coliphage with resistance to ClO2 disinfection

Functional Perturbation of the Gab2 Multiprotein Complex by High-affinity SH2-binding Monobodies in Chronic Myelogenous Leukemia

Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity

The Black cells phenotype is caused by a point mutation in the Drosophila pro-phenoloxidase 1 gene that triggers melanization and hematopoietic defects

Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis

In-depth analysis of hyaline fibromatosis syndrome frameshift mutations at the same site reveal the necessity of personalized therapy