Ligand (biochemistry)In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from Latin ligare, which means 'to bind'. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically results in a change of conformational isomerism (conformation) of the target protein. In DNA-ligand binding studies, the ligand can be a small molecule, ion, or protein which binds to the DNA double helix.
Science of LogicScience of Logic (SL; Wissenschaft der Logik, WdL), first published between 1812 and 1816, is the work in which Georg Wilhelm Friedrich Hegel outlined his vision of logic. Hegel's logic is a system of dialectics, i.e., a dialectical metaphysics: it is a development of the principle that thought and being constitute a single and active unity. Science of Logic also incorporates the traditional Aristotelian syllogism: It is conceived as a phase of the "original unity of thought and being" rather than as a detached, formal instrument of inference.
Process philosophyProcess philosophy, also ontology of becoming, or processism, is an approach in philosophy that identifies processes, changes, or shifting relationships as the only real experience of everyday living. In opposition to the classical view of change as illusory (as argued by Parmenides) or accidental (as argued by Aristotle), process philosophy posits transient occasions of change or becoming as the only fundamental things of the ordinary everyday real world.
LocalhostIn computer networking, localhost is a hostname that refers to the current computer used to access it. It is used to access the network services that are running on the host via the loopback network interface. Using the loopback interface bypasses any local network interface hardware. The local loopback mechanism may be used to run a network service on a host without requiring a physical network interface, or without making the service accessible from the networks the computer may be connected to.
Academic authorshipAcademic authorship of journal articles, books, and other original works is a means by which academics communicate the results of their scholarly work, establish priority for their discoveries, and build their reputation among their peers. Authorship is a primary basis that employers use to evaluate academic personnel for employment, promotion, and tenure. In academic publishing, authorship of a work is claimed by those making intellectual contributions to the completion of the research described in the work.
Shell (computing)In computing, a shell is a computer program that exposes an operating system's services to a human user or other programs. In general, operating system shells use either a command-line interface (CLI) or graphical user interface (GUI), depending on a computer's role and particular operation. It is named a shell because it is the outermost layer around the operating system.
DialecticDialectic (διαλεκτική, dialektikḗ; Dialektik), also known as the dialectical method, refers originally to dialogue between people holding different points of view about a subject, but wishing to arrive at the truth through reasoned argumentation. Dialectic resembles debate, but the concept excludes subjective elements such as emotional appeal and rhetoric. It has its origins in ancient philosophy and continued to be developed in the Middle Ages. In the modern period, Hegelianism refigured "dialectic" to no longer refer to a literal dialogue.
