Marfan syndromeMarfan syndrome (MFS) is a multi-systemic genetic disorder that affects the connective tissue. Those with the condition tend to be tall and thin, with long arms, legs, fingers, and toes. They also typically have exceptionally flexible joints and abnormally curved spines. The most serious complications involve the heart and aorta, with an increased risk of mitral valve prolapse and aortic aneurysm. The lungs, eyes, bones, and the covering of the spinal cord are also commonly affected. The severity of the symptoms is variable.
Vascular surgeryVascular surgery is a surgical subspecialty in which vascular diseases involving the arteries, veins, or lymphatic vessels, are managed by medical therapy, minimally-invasive catheter procedures and surgical reconstruction. The specialty evolved from general and cardiovascular surgery where it refined the management of just the vessels, no longer treating the heart or other organs. Modern vascular surgery includes open surgery techniques, endovascular (minimally invasive) techniques and medical management of vascular diseases - unlike the parent specialities.
Bolted jointA bolted joint is one of the most common elements in construction and machine design. It consists of a male threaded fastener (e. g., a bolt) that captures and joins other parts, secured with a matching female screw thread. There are two main types of bolted joint designs: tension joints and shear joints. In a tension joint, the bolt and clamped components of the joint are designed to transfer an applied tension load through the joint by way of the clamped components by the design of a proper balance of joint and bolt stiffness.
