Publication
Resolving molecule-specific information in dynamic lipid membrane processes with multi-resonant infrared metasurfaces
Related publications (34)
Effects of thermal, mechanical, and electrostatic perturbations on lipid membrane hydration investigated by second harmonic imaging
Hydrated lipid bilayer membranes are crucial components of cells and organelles, serving as the outer boundary that separates the cellular components from the extracellular environment. Lipid membranes regulate their structures and functions by dynamically ...
EPFL2023Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report
Michele De Palma, Ferdinando Pucci, Qin Zhang
Extracellular vesicles (EVs) are small, lipid-bilayer-bound particles released by cells that can contain important bioactive molecules, including lipids, RNAs, and proteins. Once released in the extracellular environment, EVs can act as messengers locally ...
WILEY2023Infrared nanoplasmonic metasurfaces augmented by artificial intelligence for universal biosensing
Nanoplasmonic metasurfaces have shown outstanding light-matter interaction enhancement capabilities, leading to their emergence as powerful platforms for highly sensitive biospectroscopy. Metasurface-enhanced biospectroscopy offers unprecedented opportunit ...
EPFL2022Water as a contrast agent for imaging interfacial structure and ion transport in giant vesicles
Hydrated lipid bilayer membranes and their asymmetry play a fundamental role in living cells by maintaining and regulating concentration gradients between cells, their environment, and their compartments. They achieve this not only through various channels ...
EPFL2022Molecular ordering effects in bulk and at lipid/water nanoscopic interfaces: A story of water, light, and order
Water is ubiquitous on Earth, playing a critical role for a plethora of structures, processes and chemical reactions in nature. Its unique physicochemical properties originate mainly from its hydrogen bond network. Despite its recognized importance, many a ...
EPFL2021pH sensing by lipids in membranes: The fundamentals of pH-driven migration, polarization and deformations of lipid bilayer assemblies
Anne-Florence Raphaëlle Bitbol
Most biological molecules contain acido-basic groups that modulate their structure and interactions. A consequence is that pH gradients, local heterogeneities and dynamic variations are used by cells and organisms to drive or regulate specific biological f ...
Elsevier BV2018Nanoparticle Liposome Interactions
Protein-mimetic materials are of great interest for biotechnology to grant protein-like properties to artificial systems. Additionally, these materials can be used to shed light on the fundamental properties of proteins in many environments. Nanoparticles, ...
EPFL2018Monitoring Membrane Lipidome Turnover by Metabolic N-15 Labeling and Shotgun Ultra-High-Resolution Orbitrap Fourier Transform Mass Spectrometry
Yury Tsybin, Konstantin Nagornov, Kristina Srzentic
Lipidomes undergo permanent extensive remodeling, but how the turnover rate differs between lipid classes and molecular species is poorly understood. We employed metabolic N-15 labeling and shotgun ultra-high-resolution mass spectrometry (sUHR) to quantify ...
Amer Chemical Soc2017Infrared Plasmonic Biosensor for Real-Time and Label-Free Monitoring of Lipid Membranes
Hatice Altug, Dordaneh Etezadi, Daniel Rodrigo Lopez, Odeta Limaj
In this work, we present an infrared plasmonic biosensor for chemical-specific detection and monitoring of biomimetic lipid membranes in a label-free and real-time fashion. Lipid membranes constitute the primary biological interface mediating cell signalin ...
American Chemical Society2016Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I
High-density lipoprotein (HDL) particles are cholesterol and lipid transport containers. Mature HDL particles destined for the liver develop through the formation of intermediate discoidal HDL particles, which are the primary acceptors for cholesterol. Her ...
Springer Nature2016