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Well-defined diazotates are scarce. Here we report the synthesis of unprecedented homoleptic palladium(II) diazotate complexes. The palladium(II)-mediated nitrosylation of 2-aminopyridines with NaNO2 results in the formation of metal-stabilized diazotates, which were found to be cytotoxic to human ovarian cancer cells.
Paul Joseph Dyson, Mylène Soudani, Catherine Marie Amélie Clavel, Emilia Paunescu
Paul Joseph Dyson, Tina Riedel, Agnese Petrini