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Structure and functionality of polyelectrolyte brushes, a surface force perspective

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Small AFM cantilevers for biological applications

Since its development in 1986, the Atomic force microscope (AFM) has become a revolutionary tool for surface analysis. AFM is of special interest to biologists because of its ability to operate in liquids. Applications include imaging molecules, cells, tis ...

2006

Q-factor optimization of a tuning-fork/fiber sensor for shear-force detection

Majed Chergui, Andrea Callegari, Jinquan Liu

We present the results of an exptl. and theor. study on the optimum design of shear-force sensors, used in scanning probe microscopes. We have optimized a configuration consisting of a tuning-fork/fiber-tip assembly, achieving quality factors (Q) exceeding ...

2005

Force spectroscopy of collagen fibers to investigate their mechanical properties and structural organization

Georg Fantner

Tendons are composed of collagen and other molecules in a highly organized hierarchical assembly, leading to extraordinary mechanical properties. To probe the cross-links on the lower level of organization, we used a cantilever to pull substructures out of ...

2004

The 2/3 power law dependence of capillary force on normal load in nanoscopic friction

Harald Brune

During the sliding of an atomic force microscope (AFM) tip on a rough hydrophilic surface, water capillary bridges form between the tip and the asperities of the sample surface. These water bridges give rise to capillary and friction forces. We show that t ...

2004

Interaction potential and hopping dynamics governing sliding friction

Harald Brune

The friction force on a nanometer-sized tip sliding on a surface is related to the thermally activated hopping of the contact atoms on an effective atomic interaction potential. A general analytical expression relates the height of this potential and the h ...

2003

Surface modification of PVC endotracheal tubes by oxygen glow discharge to reduce bacterial adhesion

Karine Triandafillu

A d.c. oxygen glow discharge was used to modify medical-grade poly(vinyl chloride) (PVC) to study how surface chemistry and hydrophilicity influence Pseudomonas aeruginosa adhesion. The effects of plasma exposure time on the resulting surface, including ch ...

Wiley-Blackwell2003

Kinetics of capillary condensation in nanoscopic sliding friction

Harald Brune

The velocity and humidity dependence of nanoscopic sliding friction has been studied on CrN and diamondlike carbon surfaces with an atomic force microscope. The surface wettability is found to be decisive. Partially hydrophilic surfaces show a logarithmic ...

2002

Local probe microscopy on lipid membranes

Many fundamental processes that govern the function of biological cells occur on or immediately under the cell membrane. Fluorescence marking of specific sites has had a large impact in the recognition of these processes. In addition, observation in an app ...

EPFL2000

Force-distance curves by atomic force microscopy

Giovanni Dietler

Atomic force microscopy (AFM) force-distance curves have become a fundamental tool in several fields of research, such as surface science, materials engineering, biochemistry and biology. Furthermore, they have great importance for the study of surface int ...

Elsevier1999

Investigation of nanolocal fluorescence resonance energy transfer for scanning probe microscopy

Majed Chergui, Giovanni Dietler

Fluorescence resonance energy transfer (FRET) was obsd. between donor dye mols. deposited onto the sample surface and acceptor dye mols. deposited onto the scanning near-field optical microscope (SNOM) or at. force microscope tip. FRET was obsd. only when ...

1999