DNA repairDNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes.
Cluster analysisCluster analysis or clustering is the task of grouping a set of objects in such a way that objects in the same group (called a cluster) are more similar (in some sense) to each other than to those in other groups (clusters). It is a main task of exploratory data analysis, and a common technique for statistical data analysis, used in many fields, including pattern recognition, , information retrieval, bioinformatics, data compression, computer graphics and machine learning.
Matrix multiplication algorithmBecause matrix multiplication is such a central operation in many numerical algorithms, much work has been invested in making matrix multiplication algorithms efficient. Applications of matrix multiplication in computational problems are found in many fields including scientific computing and pattern recognition and in seemingly unrelated problems such as counting the paths through a graph. Many different algorithms have been designed for multiplying matrices on different types of hardware, including parallel and distributed systems, where the computational work is spread over multiple processors (perhaps over a network).
High availabilityHigh availability (HA) is a characteristic of a system that aims to ensure an agreed level of operational performance, usually uptime, for a higher than normal period. Modernization has resulted in an increased reliance on these systems. For example, hospitals and data centers require high availability of their systems to perform routine daily activities. Availability refers to the ability of the user community to obtain a service or good, access the system, whether to submit new work, update or alter existing work, or collect the results of previous work.
High-availability clusterHigh-availability clusters (also known as HA clusters, fail-over clusters) are groups of computers that support server applications that can be reliably utilized with a minimum amount of down-time. They operate by using high availability software to harness redundant computers in groups or clusters that provide continued service when system components fail. Without clustering, if a server running a particular application crashes, the application will be unavailable until the crashed server is fixed.
Globular clusterA globular cluster is a spheroidal conglomeration of stars. Globular clusters are bound together by gravity, with a higher concentration of stars towards their centers. They can contain anywhere from tens of thousands to many millions of member stars. Their name is derived from Latin globulus (small sphere). Globular clusters are occasionally known simply as "globulars". Although one globular cluster, Omega Centauri, was observed in antiquity and long thought to be a star, recognition of the clusters' true nature came with the advent of telescopes in the 17th century.
Computational complexity of matrix multiplicationIn theoretical computer science, the computational complexity of matrix multiplication dictates how quickly the operation of matrix multiplication can be performed. Matrix multiplication algorithms are a central subroutine in theoretical and numerical algorithms for numerical linear algebra and optimization, so finding the right amount of time it should take is of major practical relevance. Directly applying the mathematical definition of matrix multiplication gives an algorithm that requires n3 field operations to multiply two n × n matrices over that field (Θ(n3) in big O notation).
Computer clusterA computer cluster is a set of computers that work together so that they can be viewed as a single system. Unlike grid computers, computer clusters have each node set to perform the same task, controlled and scheduled by software. The components of a cluster are usually connected to each other through fast local area networks, with each node (computer used as a server) running its own instance of an operating system. In most circumstances, all of the nodes use the same hardware and the same operating system, although in some setups (e.
Hierarchical clusteringIn data mining and statistics, hierarchical clustering (also called hierarchical cluster analysis or HCA) is a method of cluster analysis that seeks to build a hierarchy of clusters. Strategies for hierarchical clustering generally fall into two categories: Agglomerative: This is a "bottom-up" approach: Each observation starts in its own cluster, and pairs of clusters are merged as one moves up the hierarchy. Divisive: This is a "top-down" approach: All observations start in one cluster, and splits are performed recursively as one moves down the hierarchy.
Star clusterStar clusters are large groups of stars held together by self-gravitation. Two main types of star clusters can be distinguished: globular clusters are tight groups of ten thousand to millions of old stars which are gravitationally bound, while open clusters are more loosely clustered groups of stars, generally containing fewer than a few hundred members, and are often very young.
