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In this study we examined the passive biocompatibility of a three-dimensional microelectrode array (MEA), designed to be coupled to organotypic brain slice cultures for multisite recording of electrophysiological signals. Hippocampal (and corticostriatal) ...
An array of electrodes on which cells could be grown directly was fabricated using silicon anisotropic etching and a thick-photoresist process and employed for the detection of nitric oxide (NO) released from a population of adherently growing human umbili ...
A theoretical approach to the current vs. time behavior of arrays of hemispherical or disc-shaped microelectrodes is presented. The treatment includes the chronoamperometric response to changes of the applied potential, and the dynamic response to changes ...
A wide range of applications in neurotechnological research rely on planar microelectrode arrays (MEA) but the disadvantage of these systems is the low density of electrodes caused by the problem of wiring a great number of electrodes. In turn this results ...
Several multi-electrode array devices integrating planar metal electrodes were designed in the past 30 years for extracellular stimulation and recording from cultured neuronal cells and organotypic brain slices. However, these devices are not well suited f ...
In the past decade, magnetic resonance imaging (MRI) research has been focused on the acquisition of physiological and biochemical information noninvasively. Probably the most notable accomplishment in this general effort has been the introduction of the M ...
This paper describes the development of microelectrodes with integrated three-dimensional electrode structures. The integration of three-dimensional structures aims at an improvement of the electrode/tissue interface. Due to the increase in surface area th ...
This paper describes the fabrication of polyimide-based microelectrodes with embedded fluidic microchannels. The thin-film structures combine for the first time a fluidic system with microelectrodes for recording and stimulation of biological signals on a ...