Non-setting, injectable biomaterials containing particulate hydroxyapatite can increase primary stability of bone screws in cancellous bone
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Mechanical stimulus has been identified for a long time as a key player in the adaptation of the musculo-skeletal tissues to their function. Mechanical loading is then an intrinsic variable to be considered when new developments are proposed in bone tissue ...
The role of tissue-level post-yield behavior on the apparent-level strength of trabecular bone is a potentially important aspect of bone quality. To gain insight into this issue, we compared the apparent-level strength of trabecular bone for the hypothetic ...
The hip is one of the most injured joint in the body with ageing. Osteoarthritis and degenerative diseases often lead to the necessity of a total hip arthroplasty in order to reduce pain and increase mobility. The advantage of cementless implants resides i ...
Purpose. To assess the effect of external mechanical microstimuli of controlled magnitude on the microarchitecture of the peri-implant bone beds in rat tibiae. Materials and Methods. Tibiae of forty rats were fitted with two transcutaneous titanium cylinde ...
The present invention provides compounds suitable for functionalizing biomaterials, in particular prosthetics and implant materials, functionalized biomaterials, and methods for synthesizing the compound. The compounds contain an anchoring group, a group f ...
Background. Our knowledge of mandibular growth mostly derives from cephalometric radiography, which has inherent limitations due to the two-dimensional (2D) nature of measurement. Objective. To assess 3D morphological changes occurring during growth in a r ...
Implanted rat bones play a key role in studies involving fracture healing, bone diseases or drugs delivery among other themes. In most of these studies the implants integration also depends on the animal daily activity and musculoskeletal loads, which affe ...
Bone defects in revision knee arthroplasty (RKA) are often located in load-bearing regions. The goal of this study was to determine if a physiologic load could be used as an in situ osteogenic signal to the scaffolds filling the bone defects. In order to a ...
Bone mass is maintained by osteoclasts that resorb bone and osteoblasts that promote matrix deposition and mineralization. Bone homeostasis is altered in chronic inflammation as well as in post-menopausal loss of estrogen, which favors osteoclast activity ...
Bisphosphonates are known for their strong inhibitory effect on bone resorption. Their influence on bone formation however is less clear. In this study we investigated the spatio-temporal effect of locally delivered Zoledronate on peri-implant bone formati ...
