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Modeling CLiMP-63 spatio-temporal distribution and its interplay with Post-translational modification
Related publications (37)
PPARgamma activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes
Johan Auwerx, Kristina Schoonjans
It is currently thought that the effects of PPARgamma activation on glucose homeostasis may be due to the effect of this nuclear receptor on the production of adipocyte-derived signalling molecules, which affect muscle glucose metabolism. Potential signall ...
Elsevier1998The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation
Johan Auwerx, Kristina Schoonjans
The three types of peroxisome proliferator activated receptor (PPAR), alpha, beta (or delta), and gamma, each with a specific tissue distribution, compose a subfamily of the nuclear hormone receptor gene family. Although peroxisome proliferators, including ...
1996(ω-1)-Fluoroalk-(ω-1)-enoic Acids: Potential Fungicides
(w - 1)-Fluoroalk-(w - 1)-enoic acids of chain lengths C5-C15 were prepd. by consecutive bromofluorination and dehydrobromination of either alk-(w - 1)-enoic acids or alk-(w - 1)-enyl acetates, in the latter case followed by oxidn. The halogen increases th ...
1996Alkylated cellulosic membranes with enhanced albumin affinity: influence of competing proteins
4-Vinyl pyridine was grafted to the surface of the cellulosic membrane Cuprophan, and subsequently alkylated with both non-fatty acid-like C10 (GVP-C10) and fatty acid-like C16 (GVP-C16) aliphatic chains. In vitro albumin adsorption studies from single and ...
1995Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II and acyl-coenzyme A oxidase gene expression by fibrates and dietary fatty acids
The regulation by fibrates and dietary fatty acids of the hepatic gene expression of apolipoproteins (apo) A-I and A-II, the major protein constituents of high-density lipoproteins, as well as of acyl-CoA oxidase, the rate-limiting enzyme of the peroxisoma ...
1995Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter
Johan Auwerx, Kristina Schoonjans, Walter Wahli
The long-chain acyl-coenzyme A synthetase (ACS) gene gives rise to three transcripts containing different first exons preceded by specific regulatory regions A, B, and C. Exon-specific oligonucleotide hybridization indicated that only A-ACS mRNA is express ...
1995Regulation of gene expression by fatty acids and fibric acid derivatives: an integrative role for peroxisome proliferator activated receptors. The Belgian Endocrine Society Lecture 1992.
A group of receptors termed peroxisome proliferator activated receptors (PPAR), belonging to the nuclear hormone receptor supergene family, might be crucial in explaining how a diverse group of apparently unrelated chemicals induce peroxisomal proliferatio ...
1992