Publication

Impact of MCT1 Haploinsufficiency on the Mouse Retina

Pierre Magistretti, Sylvain Eric Lengacher, Luc Pellerin
2018
Conference paper

Abstract

The monocarboxylate transporter 1 (MCT1) is highly expressed in the outer retina, suggesting that it plays a critical role in photoreceptors. We examined MCT1+/- heterozygotes, which express half of the normal complement of MCT1. The MCT1(+/-) retina developed normally and retained normal function, indicating that MCT1 is expressed at sufficient levels to support outer retinal metabolism.

Official source

https://infoscience.epfl.ch/record/262237?ln=en

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Impact of MCT1 Haploinsufficiency on the Mouse Retina

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