Neural Circuits for Goal-Directed Sensorimotor Transformations

Sylvain Crochet, Seung-Hee Lee, Carl Petersen
ELSEVIER SCIENCE LONDON, 2019
Journal paper

Abstract

Precisely wired neuronal circuits process sensory information in a learning- and context-dependent manner in order to govern behavior. Simple sensory decision-making tasks in rodents are now beginning to reveal the contributions of distinct cell types and brain regions participating in the conversion of sensory information into learned goal-directed motor output. Task learning is accompanied by target specific routing of sensory information to specific downstream cortical regions, with higher-order cortical regions such as the posterior parietal cortex, medial prefrontal cortex, and hippocampus appearing to play important roles in learning- and context-dependent processing of sensory input. An important challenge for future research is to connect cell-type-specific activity in these brain regions with motor neurons responsible for action initiation.

Official source

https://infoscience.epfl.ch/record/263423?ln=en

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