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Related publications (32)

Diamond-Based Nanoscale Quantum Relaxometry for Sensing Free Radical Production in Cells

Diamond magnetometry makes use of fluorescent defects in diamonds to convert magnetic resonance signals into fluorescence. Because optical photons can be detected much more sensitively, this technique currently holds several sensitivity world records for r ...

WILEY-V C H VERLAG GMBH2022

Variability and reproducibility of multi-echo T2 relaxometry: Insights from multi-site, multi-session and multi-subject MRI acquisitions

Jean-Philippe Thiran, Friedhelm Christoph Hummel, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Gabriel Girard, Elda Fischi Gomez, Gian Franco Piredda, Thomas Yu, Takuya Morishita

Quantitative magnetic resonance imaging (qMRI) can increase the specificity and sensitivity of conventional weighted MRI to underlying pathology by comparing meaningful physical or chemical parameters, measured in physical units, with normative values acqu ...

2022

3-Dimensional Fluid and White Matter Suppression Magnetic Resonance Imaging Sequence Accelerated With Compressed Sensing Improves Multiple Sclerosis Cervical Spinal Cord Lesion Detection Compared With Standard 2-Dimensional Imaging

Tobias Kober

Objectives Fluid and white matter suppression (FLAWS) is a recently proposed magnetic resonance sequence derived from magnetization-prepared 2 rapid acquisition gradient-echo providing 2 coregistered datasets with white matter- and cerebrospinal fluid-supp ...

LIPPINCOTT WILLIAMS & WILKINS2022

Event-driven acquisition for content-enriched microscopy

Suliana Manley, Dora Mahecic, Willi Leopold Stepp, Chen Zhang, Martin Weigert, Juliette Griffie

Event-driven acquisition uses neural-network-based recognition of specific biological events to trigger switching between slow and fast super-resolution imaging, enriching the capture of interesting events with high spatiotemporal resolution. A common goal ...

2022

Learning to sample in Cartesian MRI

Thomas Sanchez

Magnetic Resonance Imaging (MRI) is a non-invasive, non-ionizing imaging modality with unmatched soft tissue contrast. However, compared to imaging methods like X-ray radiography, MRI suffers from long scanning times, due to its inherently sequential acqui ...

EPFL2022

Real-time shimming with FID navigators

Tobias Kober

Purpose: To implement a method for real-time field control using rapid FID navigator (FIDnav) measurements and evaluate the efficacy of the proposed approach for mitigating dynamic field perturbations and improving T-2*-weighted image quality. ...

WILEY2022

Sensor-integrated ultraflexible endovascular devices

Lucio Feo Pancaldi-Giubbini

Medical interventions in the central nervous system (CNS) are challenging due to the complexity and delicacy of the brain tissue. Techniques that do not require opening the skull would alleviate patient discomfort and increase post-operative outputs. Vesse ...

EPFL2022

Simulated Half-Fourier Acquisitions Single-shot Turbo Spin Echo (HASTE) of the Fetal Brain: Application to Super-Resolution Reconstruction

Meritxell Bach Cuadra, Tobias Kober, Tom Hilbert, Thomas Yu, Reto Meuli, Sébastien Tourbier, Patric Hagmann, Hamza Kebiri

Accurate characterization of in utero human brain maturation is critical as it involves complex interconnected structural and functional processes that may influence health later in life. Magnetic resonance imaging is a powerful tool complementary to the u ...

SPRINGER INTERNATIONAL PUBLISHING AG2021

Methods to Enhance Nuclear Magnetic Resonance Sensitivity at High Magnetic Field

Claudia Christina Zanella

MR is a well-established technique routinely used in preclinical and clinical studies. This thesis focussed on the improvement of sensitivity of different methods in MR. Hyperpolarized 129Xe gas is used for studying pulmonary disease or cerebral perfusion ...

EPFL2021

Mechanistic studies of DNP and applications of hyperpolarized probes to study renal physiology and metabolism

Alice Radaelli

Dissolution dynamic nuclear polarization (dDNP) is a powerful technique that enhances the magnetic resonance signal of nuclear spins by several orders of magnitude. DNP relies on the principle of cross-relaxation by electron spins driven out of equilibrium ...

EPFL2021

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