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The preparation of the polyketide natural products anguinomycin C and D is reported based on key steps such as Negishi stereoinversion cross coupling, Jacobsen Cr(III)-catalyzed Hetero Diels−Alder reaction, Evans B-mediated syn-aldol chemistry, and B-alkyl ...
Scanning probe microscopy has become, nowadays, a branch of microscopy widely used to image surfaces of different specimens. Among the various applications, the magnetic imaging is one of the most exciting scanning probe microscopy techniques. It allows th ...
Images directly visualizing the spatial spin-diffusion process are reported. The measurements were performed using a magnetic resonance force microscope. The field gradient associated with the forcedetection experiment is large enough to affect the spin dy ...
The atomic force microscope (AFM) is limited in imaging speed by the bandwidth and dynamic behavior of the actuators and mechanical parts. For high-speed imaging all AFM components have to be optimized in performance. Here, we present improvements of the f ...
Mol. dynamics simulations (MDS) of the structural rearrangements on the pathway leading to procaspase 3 (I) activation are presented. A retrostructural approach was used to build I from mature caspase 3 (II). The peptide bond that was cleaved during enzyme ...
Since its development in 1986, the Atomic force microscope (AFM) has become a revolutionary tool for surface analysis. AFM is of special interest to biologists because of its ability to operate in liquids. Applications include imaging molecules, cells, tis ...
This special issue contains a selection of invited, full-length, peer-reviewed manuscripts from participants of the international workshop “Water in Pavements WIP’05”, held in Madrid, Spain on 27th October 2005. The presented papers give a complete picture ...
A review on isolated cationic and neutral homoat. heavier group 15 cages and clusters, charged or non-charged assemblies of two or more elemental atoms E (E = P, As, Sb, Bi) without stabilizing (bulky) ligands. It focuses on the recent developments in the ...
Tissue transglutaminase (tTG) has been implicated in the pathogenesis of Parkinson disease (PD). However, exactly how tTG modulates the structural and functional properties of alpha-synuclein (alpha-syn) and contributes to the pathogenesis of PD remains un ...
American Society for Biochemistry and Molecular Biology2009
Innovative surface imaging techniques allowing parallel magnetic and topographical microscopy with nanometer scale spatial resolution are developed in this project. Nanometer scale magnetosensitive devices on Atomic Force Microscopy (AFM) tips will be stud ...