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Linking a mutation to survival in wild mice

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An Approximate Markov Model for the Wright-Fisher Diffusion and Its Application to Time Series Data

Jeffrey David Jensen, Anna Ferrer Admetlla

The joint and accurate inference of selection and demography from genetic data is considered a particularly challenging question in population genetics, since both process may lead to very similar patterns of genetic diversity. However, additional informat ...

Genetics Society America2016

A central focus of population genetics has been examining the contribution of selective and neutral processes in shaping patterns of intraspecies diversity. In terms of selection specifically, surveys of higher organisms have shown considerable variation i ...

Wiley-Blackwell2016

Detecting spatial genetic signatures of local adaptation in heterogeneous landscapes

Stéphane Joost

The spatial structure of the environment (e.g., the configuration of habitat patches) may play an important role in determining the strength of local adaptation. However, previous studies of habitat heterogeneity and local adaptation have largely been limi ...

Wiley-Blackwell2016

Background: Microsporidia are spore-forming obligate intracellular parasites that include both emerging pathogens and economically important disease agents. However, little is known about the genetic diversity of microsporidia. Here, we investigated patter ...

Biomed Central Ltd2016

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During his well-known debate with Fisher regarding the phenotypic dataset of Panaxia dominula, Wright suggested fluctuating selection as a potential explanation for the observed change in allele frequencies. This model has since been invoked in a number of ...

Genetics Society of America2016

Catch Me if You Can: Adaptation from Standing Genetic Variation to a Moving Phenotypic Optimum

Sebastian Matuszewski

Adaptation lies at the heart of Darwinian evolution. Accordingly, numerous studies have tried to provide a formal framework for the description of the adaptive process. Of these, two complementary modeling approaches have emerged: While so-called adaptive- ...

2015

Background In wild plant populations, genetic divergence within continuous stands is common, sometimes at very short geographical scales. While restrictions to gene flow combined with local inbreeding and genetic drift may cause neutral differentiation amo ...

Public Library of Science2015

Internet, espace et société. Changer l’espace, changer la société

Boris Beaude

Avec Internet, l’espace a tant changé que la société est animée d’un mouvement dont la dynamique est peu lisible, car peu familière. Nier la réalité et la spatialité d’Internet expose à la déréalisation de nombre d’actions qui contribuent remarquablement à ...

2015

Symmetry-breaking transitions associated with the buckling and folding of curved multilayered surfaces—which are common to a wide range of systems and processes such as embryogenesis, tissue differentiation and structure formation in heterogeneous thin fil ...

Nature Publishing Group2015

Genome-wide patterns of adaptation to climate-mediated selective pressures in sheep

Stéphane Joost, Sylvie Stucki

Sheep (Ovis aries) have been well adapted to thrive in a diverse range of climates during the domestication and breed development process. These climate-mediated selective pressures have shown to influence phenotypic variation within and among breeds and, ...

2014