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Engineering Stem Cell Self-organization to Build Better Organoids

Related publications (36)

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Annual Report 2014, School of Engineering (STI) Services and Collections

Béatrice Marselli Fuerer, Pascale Claudine Giraud Bouton

This report proposes an overview of the activities and services provided by the library to the School of engineering (STI) in 2014 as well as the STI collection accessible at the Library. It also presents the main projects that will be continued or initiat ...

Bibliothèque de l'EPFL2015

New Tools for Hydrogel-Based 3D Bioprinting

Andrea Negro

The in vitro recapitulation of tissue and organ function represents one of the main objectives of tissue engineering. Developments in this field have numerous applications, from alleviating the shortage of donor organs to providingmore representative pla ...

EPFL2014

Bioengineering approaches to guide stem cell-based organogenesis

Matthias Lütolf, Adrian Ranga, Nikolche Gjorevski

During organogenesis, various molecular and physical signals are orchestrated in space and time to sculpt multiple cell types into functional tissues and organs. The complex and dynamic nature of the process has hindered studies aimed at delineating morpho ...

Company of Biologists2014

The long-term risk of malignancy associated with stem cell therapies is a significant concern in the clinical application of this exciting technology. We report a cancer-selective strategy to enhance the safety of stem cell therapies. Briefly, using a cell ...

Elsevier2014

Micro-engineering the Cerebral Cortical Cell Niche

Anja Kunze

A major problem in traditional cell culture methods, such as Petri dishes and culture flasks, is the very simplified artificial environment around the cells. Traditional cell culture methods lack features of the native cell niche, such as gradients and cel ...

EPFL2012

Definition of in Vitro Microenvironments to Characterize and Control Pancreatic Progenitor Expansion and Differentiation

Chiara Greggio

The pancreas plays a central role in metabolism. The exocrine pancreas, composed of ductal and acinar cells, secretes and delivers digestive enzymes into the duodenum where they contribute to food digestion. The endocrine pancreas, constituted by the islet ...

EPFL2011

Production of biofuels and biochemicals: in need of an ORACLE

Vassily Hatzimanikatis, Ljubisa Miskovic

The engineering of cells for the production of fuels and chemicals involves simultaneous optimization of multiple objectives, such as specific productivity, extended substrate range and improved tolerance – all under a great degree of uncertainty. The achi ...

Elsevier2010

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Hydrodynamics of gas-liquid systems has been studied by high-speed camera. The flow patterns of CO2/water-based fluids were investigated in three glass microreactors having different geometries. Four main regimes were observed: bubbly, slug, slug-annular a ...

Elsevier2010

The e-puck, a Robot Designed for Education in Engineering

Dario Floreano, Alcherio Martinoli, Francesco Mondada, Jean-Christophe Zufferey, Michael Bonani, Stéphane Magnenat, James Pugh, Adam Klaptocz, Christopher Cianci, Xavier Raemy

Mobile robots have the potential to become the ideal tool to teach a broad range of engineering disciplines. Indeed, mobile robots are getting increasingly complex and accessible. They embed elements from diverse ﬁelds such as mechanics, digital electronic ...

IPCB: Instituto Politécnico de Castelo Branco2009

Whole-cell bioprocessing of human fetal cells for tissue engineering of skin

Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri

Current restrictions for human cell-based therapies have been related to technological limitations with regards to cellular proliferation capacity (simple culture conditions), maintenance of differentiated phenotype for primary human cell culture and trans ...

2009