Publication
Discovery and validation of temporal patterns involved in human brain ketometabolism in cerebral microdialysis fluids of traumatic brain injury patients
Related publications (34)
Safety, tolerability and blinding efficiency of non-invasive deep transcranial temporal interference stimulation: first experience from more than 250 sessions
Friedhelm Christoph Hummel, Pierre Theopistos Vassiliadis, Elena Beanato, Fabienne Windel, Emma Marie D Stiennon, Maximilian Jonas Wessel
Objective. Selective neuromodulation of deep brain regions has for a long time only been possible through invasive approaches, because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques. Approach. An appr ...
Bristol2024Cerebral Metabolic Dysfunction at the Acute Phase of Traumatic Brain Injury Correlates with Long-Term Tissue Loss
Adriano Bernini, Ricardo Alberto Corredor Jerez, Neil Graham
Following traumatic brain injury (TBI), cerebral metabolic dysfunction, characterized by an elevated cerebral microdialysis (CMD) lactate/pyruvate (LP) ratio, is associated with poor outcome. However, the exact pathophysiological mechanisms underlying this ...
MARY ANN LIEBERT, INC2022Grape polyphenols decrease circulating branched chain amino acids in overfed adults
Jörg Hager, José Luis Abelleira Fernández, Sofia Moco
Introduction and aimsDietary polyphenols have long been associated with health benefits, including the prevention of obesity and related chronic diseases. Overfeeding was shown to rapidly induce weight gain and fat mass, associated with mild insulin resist ...
FRONTIERS MEDIA SA2022Label-Efficient Volumetric Deep Semantic Segmentation of Intracranial Hemorrhages
Traumatic brain injuries is one of the major cause of death and disability worldwide especially among young people. The initial injury can later develop into a secondary injury that is particularly lethal. The patient’s survival relies on fast and proper a ...
2021New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases
Jian Wang, Friedhelm Christoph Hummel
The past decade has brought tremendous progress in diagnostic and therapeutic options for cerebrovascular diseases as exemplified by the advent of thrombectomy in ischemic stroke, benefitting a steeply increasing number of stroke patients and potentially p ...
2021Forecasting intracranial hypertension using multi-scale waveform metrics
Objective: Acute intracranial hypertension is an important risk factor of secondary brain damage after traumatic brain injury. Hypertensive episodes are often diagnosed reactively, leading to late detection and lost time for intervention planning. A pro-ac ...
IOP PUBLISHING LTD2020PEXO - A Pediatric Whole Hand Exoskeleton for Grasping Assistance in Task-Oriented Training
Roger Gassert, Olivier Lambercy
Children with hand motor impairment due to cerebral palsy, traumatic brain injury, or pediatric stroke are considerably affected in their independence, development, and quality of life. Treatment conventionally includes task-oriented training in occupation ...
2019Gangliosides: Treatment Avenues in Neurodegenerative Disease
Gangliosides are cell membrane components, most abundantly in the central nervous system (CNS) where they exert among others neuro-protective and -restorative functions. Clinical development of ganglioside replacement therapy for several neurodegenerative ...
FRONTIERS MEDIA SA2019Hypertonic Lactate to Improve Cerebral Perfusion and Glucose Availability After Acute Brain Injury
Pierre Magistretti, Jocelyne Bloch
Objectives: Lactate promotes cerebral blood flow and is an efficient substrate for the brain, particularly at times of glucose shortage. Hypertonic lactate is neuroprotective after experimental brain injury; however, human data are limited. Design: Prospec ...
LIPPINCOTT WILLIAMS & WILKINS2018Central nervous system microbleeds in the acute phase are associated with structural integrity by DTI one year after mild traumatic brain injury: A longitudinal study
Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Pietro Bontempi
Introduction: Several imaging modalities are under investigation to unravel the pathophysiological mystery of delayed performance deficits in patients after mild traumatic brain injury (mTBI). Although both imaging and neuropsychological studies have been ...
ELSEVIER URBAN & PARTNER SP Z O O2018