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Open Source Brain: A Collaborative Resource for Visualizing, Analyzing, Simulating, and Developing Standardized Models of Neurons and Circuits

Related publications (46)

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Impact of Networked Cognition and Learning on Engineered Systems [Further Thoughts]

Ali H. Sayed

The research community is witnessing expansive efforts aimed at understanding one of the most wondrous manifestations of cognition in nature. The Blue Brain Project and the Human Brain Project in Europe are examples of ambitious drives aimed at building a ...

Institute of Electrical and Electronics Engineers2014

The In-Silico Neocortical Microcircuit

Michael Reimann

The neocortex is one of the most important brain regions, occupying more than 80% of the brain volume in mammals and contributing massively to its capability of perceiving and interpreting then environment. While it has been extensively studied, it is stil ...

EPFL2014

Longitudinal analysis of brain network reorganization in preterm IUGR children at 1, 6 and 9 years-old

Jean-Philippe Thiran, Elda Fischi Gomez

Intrauterine Growth Restriction (IUGR) due to placental insufficiency affects 5-10% of all pregnancies and it is associated with a wide range of short and long-term neurodevelopmental disorders. Different approaches have been considered to understand IUGR ...

2014

Interoperable atlases of the human brain

Sean Lewis Hill

The last two decades have seen an unprecedented development of human brain mapping approaches at various spatial and temporal scales. Together, these have provided a large fundus of information on many different aspects of the human brain including micro- ...

Elsevier2014

Neuroscience thinks big (and collaboratively)

Henry Markram

Despite cash-strapped times for research, several ambitious collaborative neuroscience projects have attracted large amounts of funding and media attention. In Europe, the Human Brain Project aims to develop a large-scale computer simulation of the brain, ...

Nature Publishing Group2013

Computational Neuroscience Breakthroughs Through Innovative Data Management

Anastasia Ailamaki, Thomas Heinis, Farhan Tauheed, Sadegh Heyrani Nobari, Laurynas Biveinis

Simulations have become key in many scientific disciplines to better understand natural phenomena. Neuroscientists, for example, build and simulate increasingly fine grained models (including subcellular details, e.g., neurotransmitter) of the neocortex to ...

2013

Seven challenges for neuroscience

Henry Markram

Although twenty-first century neuroscience is a major scientific enterprise, advances in basic research have not yet translated into benefits for society. In this paper, I outline seven fundamental challenges that need to be overcome. First, neuroscience h ...

2013

High-performance and site-directed in utero electroporation by a triple-electrode probe

Diego Ghezzi

From its introduction, in utero electroporation has arisen as a powerful tool to manipulate neural-precursor cells of the parietal cortex and their progeny in vivo. Although this technique has unlimited potentials for targeting numerous brain areas, the ex ...

2012

High-performance and site-directed in utero electroporation by a triple-electrode probe

Diego Ghezzi

In utero electroporation is a powerful tool to transfect and manipulate neural-precursor cells of the rodent parietal cortex and their progeny in vivo. Although this technique can potentially target numerous brain areas, reliability of transfection in some ...

2012

Predictive Engineering the Membrane Composition of Neocortical Neurons

Georges Khazen

The brain is the most mysterious and intricate biological structure known to man. It dominates the way we live, think, reason and behave. It is built of billions of neurons that communicate with each other through trillions of connections using electrical ...

EPFL2011