A 1D computer model of the arterial circulation in horses: An important resource for studying global interactions between heart and vessels under normal and pathological conditions
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This thesis is intended to contribute to the field of biomechanics of growth and remodeling of arteries. The work focuses particularly on growth and remodeling caused by sustained hypertension, increased blood flow, and ageing. A structure-based constituti ...
A distributed model of the human arterial tree including all main systemic arteries coupled to a heart model is developed. The one-dimensional (1-D) form of the momentum and continuity equations is solved numerically to obtain pressures and flows throughou ...
Due to the pulsatile nature of blood flow, arteries are constantly exposed to dynamic mechanical forces; the pulsatility continuously stretches the vessel wall and the flow creates a frictional force on the interior surface. These stresses, referred to as ...
The intent of this thesis is to study the function of elastin in cerebral arteries, its contribution into the aging process and its implication into different cerebral diseases and in particular cerebral aneurysms. As of today, little is known on the genes ...
Research and development was conducted on a prototype timber bridge technology developed for rural bridge sites. The work included conception, computer modeling, laboratory load tests of a reduced size specimen, field construction of a pilot bridge and fie ...
Purpose: Connecting outflow cannula of LVAD to the aorta is an underexplored issue but may have considerable impact. In fact the hemodynamic modifications due to implantation in this region can cause thromboembolic events. It is therefore important to unde ...
Previous theoretical models of arterial remodeling in response to changes in blood flow were based on the assumption that material properties of the arterial wall remain unchanged during the remodeling process. According to experimental findings, however, ...
While the role of hemodynamic variables on the development of intimal hyperplasia in arteriovenous fistulas for hemodialysis has been examined, less is known about the intramural biomechanical factors. In this study, arteriovenous fistulas were created by ...
Aims Atrial fibrillatory cycle length (AFCL) is generally accepted as a surrogate marker for local refractoriness. In this study, a computer model and clinical data on human subjects undergoing catheter ablation for paroxysmal and persistent AF were used t ...
The mechanical interactions between heart contraction and perfusion of the heart are difficult to study in humans because of the restrictions in inducing changes in hemodynamic and cardiac mechanics parameters during catheterization. We hypothesize that th ...