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Repair as Practice and Knowledge. An Ethnography of Two Repair Cafés

Related publications (32)

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A chemical biology approach to decipher chromatin ubiquitylation by RNF168

Pauline Franz

DNA damage signaling following DNA double-strand breaks (DSBs) involves numerous regulating proteins, which dynamically recognize ('read') and alter ('write' or 'erase') histone post-translational modifications (PTMs). Among these PTMs, the ubiquitin syste ...

EPFL2024

DATED: GUIDELINES FOR CREATING SYNTHETIC DATASETS FOR ENGINEERING DESIGN APPLICATIONS

Jürg Alexander Schiffmann, Cyril Picard, Faez Ahmed

Exploiting the recent advancements in artificial intelligence, showcased by ChatGPT and DALL-E, in real-world applications necessitates vast, domain-specific, and publicly accessible datasets. Unfortunately, the scarcity of such datasets poses a significan ...

Amer Soc Mechanical Engineers2023

Preomic profile of BxPC-3 cells after treatment with BRC4

Andrea Cavalli

BRCA2 and RAD51 are two proteins that play a central role in homologous recombination (HR) and DNA double strand break (DSB) repair. BRCA2 assists RAD51 fibrillation and defibrillation through binding with its eight BRC repeats, with BRC4 being one of the ...

ELSEVIER2023

Telomeres are nucleoprotein structures at the ends of linear chromosomes, being essential for the maintenance of genomic integrity. Telomeres have a unique structure which distinguishes chromosome termini from DNA damage sites. Shelterin complexes are the ...

EPFL2023

Identification and characterization of proteins that protect human telomeres from fragility

Anna Christina Näger

Difficulties to replicate telomeres - the ends of our chromosomes - can cause telomere shortening andgenome instability. These difficulties are due to the repetitive DNA sequence and distinct structures at telomeresthat challenge the semi-conservative DNA ...

EPFL2022

In the last decades, soil bioengineering has gained considerable popularity worldwide, especially in hillslope, riverbank, and earth embankment stabilisation works. The use of plants as a building material transfers the plant multifunctionality within engi ...

2021

The paper presents a comprehensive review of fundamentals and engineering applications of CO2 flow boiling heat transfer, flow patterns and two-phase pressure drops in macro- and micro-channel evaporators. First, distinctions of macro- and micro-channels a ...

PERGAMON-ELSEVIER SCIENCE LTD2021

The Industrialization of Astronomical Instrumentation: An Industrial Systems and Process Engineering Perspective

Jean-Paul Richard Kneib, Mohamed Bouri, Ricardo Jorge Araùjo Pereira, Luzius Gregor Kronig, Loïc Grossen

The Sloan Digital Sky Survey V (SDSS-V) is an all-sky spectroscopic survey of > 6 million objects, designed to decode the history of the Milky Way, reveal the inner workings of stars, investigate the origin of solar systems, and track the growth of superma ...

SPIE-INT SOC OPTICAL ENGINEERING2020

Double-strand breaks (DSBs) are the most toxic type of DNA lesions. Cells repair these lesions using either end protection- or end resection-coupled mechanisms. To study DSB repair choice, we present the Color Assay Tracing-Repair (CAT-R) to simultaneously ...

2020

SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres

Joachim Lingner, Wareed Ahmed, Verena Pfeiffer, Marianna Feretzaki, Aleksandra Vancevska

Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) has been implicated in X-chromosome inactivation, imprinting, and DNA damage repair, and mutations in SMCHD1 can cause facioscapulohumeral muscular dystrophy. More re ...

WILEY2020