Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
New enantiomerically pure alleno-acetylenic macrocycles were prepd. by oxidative homocoupling of optically active 1,3-diethynylallenes. Enantiomer sepn. resulted from a combined strategy of synthesis and chiral HPLC techniques. Two other achiral stereoisomers were also isolated and fully characterized. In addn., the X-ray structures of the chiral D4- and C2-sym. macrocycles are reported. The chiroptical properties of these macrocycles are discussed on the basis of quantum chem. calcns., by using the CAM-B3LYP functional. Studies were carried out to investigate the vibronic fine structure obsd. exptl. in the UV/Vis and CD spectra. The origin of the intense chiroptical response of the chiral alleno-acetylenic macrocycles is explained by considering the topol. of the MOs involved, thus relating electronic properties to structural features. Further anal. of the canonical MOs and the electron localization function (ELF) shows that these macrocycles belong to a relatively rare class of highly stable and formally anti-arom. Hueckel compds.
Hatice Altug, Felix Ulrich Richter, Yasaman Jahani, Rui Lu, Bang Hyun Lee, Ming-Lun Tseng, Longfang Ye
Majed Chergui, Oliviero Cannelli, Giulia Fulvia Mancini, Malte Oppermann, Camila Bacellar Cases Da Silveira, Dominik Kinschel, Christian David, Jérôme Lacour