LiverThe liver is a major metabolic organ only found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it is located in the right upper quadrant of the abdomen, below the diaphragm and mostly shielded by the lower right rib cage. Its other metabolic roles include carbohydrate metabolism, the production of hormones, conversion and storage of nutrients such as glucose and glycogen, and the decomposition of red blood cells.
Literal translationLiteral translation, direct translation, or word-for-word translation is a translation of a text done by translating each word separately without looking at how the words are used together in a phrase or sentence. In translation theory, another term for literal translation is metaphrase (as opposed to paraphrase for an analogous translation). It is to be distinguished from an interpretation (done, for example, by an interpreter). Literal translation leads to mistranslation of idioms, which was once a serious problem for machine translation.
Thoracic ductIn human anatomy, the thoracic duct (also known as the left lymphatic duct, alimentary duct, chyliferous duct, and Van Hoorne's canal) is the larger of the two lymph ducts of the lymphatic system (the other being the right lymphatic duct). The thoracic duct usually begins from the upper aspect of the cisterna chyli, passing out of the abdomen through the aortic hiatus into first the posterior mediastinum and then the superior mediastinum, extending as high up as the root of the neck before descending to drain into the systemic (blood) circulation at the venous angle.
Germ theory of diseaseThe germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can cause disease. These small organisms, too small to be seen without magnification, invade humans, other animals, and other living hosts. Their growth and reproduction within their hosts can cause disease. "Germ" refers to not just a bacterium but to any type of microorganism, such as protists or fungi, or even non-living pathogens that can cause disease, such as viruses, prions, or viroids.
Thoracic diaphragmThe thoracic diaphragm, or simply the diaphragm (ˈdaɪəfɹæm; diáphragma), is a sheet of internal skeletal muscle in humans and other mammals that extends across the bottom of the thoracic cavity. The diaphragm is the most important muscle of respiration, and separates the thoracic cavity, containing the heart and lungs, from the abdominal cavity: as the diaphragm contracts, the volume of the thoracic cavity increases, creating a negative pressure there, which draws air into the lungs.
Enterohepatic circulationEnterohepatic circulation refers to the circulation of biliary acids, bilirubin, drugs or other substances from the liver to the bile, followed by entry into the small intestine, absorption by the enterocyte and transport back to the liver. Enterohepatic circulation is an especially important concept in the field of toxicology as many lipophilic xenobiotics undergo this process causing repeated liver damage. Hepatocytes metabolize cholesterol to cholic acid and chenodeoxycholic acid.
Inferior vena cavaThe inferior vena cava is a large vein that carries the deoxygenated blood from the lower and middle body into the right atrium of the heart. It is formed by the joining of the right and the left common iliac veins, usually at the level of the fifth lumbar vertebra. The inferior vena cava is the lower ("inferior") of the two venae cavae, the two large veins that carry deoxygenated blood from the body to the right atrium of the heart: the inferior vena cava carries blood from the lower half of the body whilst the superior vena cava carries blood from the upper half of the body.
Portal venous systemIn the circulatory system of vertebrates, a portal venous system occurs when a capillary bed pools into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. Most capillary beds drain into venules and veins which then drain into the heart, not into another capillary bed. There are three portal venous systems – the hepatic portal system, the hypophyseal portal system, and the renal portal system.
