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Imaging methods to capture the beating and developing heart inside embryonic animal models such as the zebrafish are a key component for the study of fundamental biological processes such as cardiac birth defects or tissue regeneration. However, live heart ...
Non fungible tokens (NFTs) are used to define the ownership of digital assets. More recently, there has been a surge of platforms to auction digital art as well as other digital assets in form of image, video, and audio content of all sorts. Although NFTs ...
Humans are comparison machines: comparing and choosing an item among a set of alternatives (such as objects or concepts) is arguably one of the most natural ways for us to express our preferences and opinions. In many applications, the analysis of data con ...
We address the problem of learning a ranking by using adaptively chosen pairwise comparisons. Our goal is to recover the ranking accurately but to sample the comparisons sparingly. If all comparison outcomes are consistent with the ranking, the optimal sol ...
We developed a method for the fast sorting and selection of mammalian cells expressing and secreting a protein at high levels. This procedure relies on cell capture using an automated microfluidic device handling antibody-coupled magnetic microparticles an ...
Proprotein Convertases (PCs) constitute a family of serine proteases that activate various
hormones, growth factors and cell adhesion molecules by mediating endoproteolytic cleavage
of their secreted inactive precursors during their transit in the secret ...
Fluorescence-activated droplet sorting (FADS) has become a widely used technique for high-throughput screening applications. However, existing methods are very sensitive to fluctuating flow rates at the sorting junction, which can be caused by the pulsing ...
Methods of topological data analysis have been successfully applied in a wide range of fields to provide useful summaries of the structure of complex data sets in terms of topological descriptors, such as persistence diagrams. While there are many powerfu ...
2020
Analyzing surface epitopes of single HIV particles holds great potential for the development of vaccine candidates. However, existing technologies do not allow corresponding screens at high throughput. We present here a single-virus droplet-based microflui ...
2017
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Log-structured merge (LSM) data stores enable to store and process large volumes of data while maintaining good performance. They mitigate the I/O bottleneck by absorbing updates in a memory layer and transferring them to the disk layer in sequential batch ...