Methods of treating or preventing an aging-related disease
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The invention relates generally to methods, agents and pharmaceutical compositions for treating or preventing an aging-related disease by reducing the levels and/or activity of the RNA-binding protein PUM2.
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An aging-associated disease (commonly termed age-related disease, ARD) is a disease that is most often seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself because all adult animals age (with rare exceptions) but not all adult animals experience all age-associated diseases. The term does not refer to age-specific diseases, such as the childhood diseases chicken pox and measles, only diseases of the elderly.
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