Publication
Corticolumbar dynamics during recovery after spinal cord injury
Related publications (104)
Hand exoskeleton for rehabilitation and assistance of hand motor functions
A device and system for e.g. rehabilitation and assistance of hand motor functions, in particular a portable and underactuated hand exoskeleton for use in activities of daily living, is disclosed. ...
2022Electrical spinal cord stimulation protocols to regulate motor and autonomic functions in people with neurological disorders
Neurological disorders such as spinal cord injury (SCI) massively reduce independence and quality of life. Most often, the majority of the nervous system is still fully or partially spared, but dysfunctional due to aberrant or absent descending input from ...
EPFL2021Modeling spinal locomotor circuits for movements in developing zebrafish
Many spinal circuits dedicated to locomotor control have been identified in the developing zebrafish. How these circuits operate together to generate the various swimming movements during development remains to be clarified. In this study, we iteratively b ...
eLIFE SCIENCES PUBL LTD2021Spinal V1 neurons inhibit motor targets locally and sensory targets distally
Rostro-caudal coordination of spinal motor output is essential for locomotion. Most spinal interneurons project axons longitudinally to govern locomotor output, yet their connectivity along this axis remains unclear. In this study, we use larval zebrafish ...
CELL PRESS2021Personalizable computational models of electrical spinal cord stimulation to restore function after neurological disorders
Spinal Cord Injury (SCI) disrupts the communication between the brain and spinal circuits below the lesion, leading to a plethora of neurological impairments, including the loss of motor function. At present, the only medical practices to enhance recovery ...
EPFL2021Development of a peripheral neuroprosthesis to elicit fine hand movements in primates
Marion Aimée Geneviève Badi-Dubois
Neurological disorders such as spinal cord lesion and stroke disturb sensorimotor pathways and result in severe motor deficits that can dreadfully impact the quality of life of affected individuals. Strategies aiming at restoring hand function after upper- ...
EPFL2021Combining Optogenetic Stimulation and Motor Training Improves Functional Recovery and Perilesional Cortical Activity
Silvestro Micera, Maria Pasquini, Francesco Saverio Pavone
Background. An ischemic stroke is followed by the remapping of motor representation and extensive changes in cortical excitability involving both hemispheres. Although stimulation of the ipsilesional motor cortex, especially when paired with motor training ...
SAGE PUBLICATIONS INC2021Central and peripheral mechanisms: a multimodal approach to understanding and restoring human motor control
All human actions involve motor control. Even the simplest movement requires the coordinated recruitment of many muscles, orchestrated by neuronal circuits in the brain and the spinal cord. As a consequence, lesions affecting the central nervous system, su ...
EPFL2020Decoding of grasping tasks from intraneural recordings in trans-radial amputee
Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle
Objective. A major challenge in neuroprosthetics is the restoration of sensory-motor hand functions in upper-limb amputees. Neuroprostheses based on the direct re-connection of the peripheral nerves may be an interesting approach for re-establishing the na ...
2020Axon regeneration and circuit reorganization after complete spinal cord injury
First human trials involving neuroprosthetic rehabilitation demonstrated recently that significant
functional benefits can be achieved with lumbosacral neuromodulation and reorganized
spared projections. However, complete spinal cord injuries (SCI) wholly ...
EPFL2019