Crystal Structures of Limulus SAP-Like Pentraxin Reveal Two Molecular Aggregations
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Calcium regulates neuronal signaling and viability through a vast range of cellular and molecular mechanisms. However, many details of these mechanisms still remain to be elucidated. It is believed that calcium-related pathways may comprise promising thera ...
Ca2+ plays a crucial role in cell communication. For example, periodical changes in Ca2+ concentration act as cell sig- nals. Intracellular Ca2+ signals have been measured by Ca2+ sensitive fluorescent dye [1]. In this study, extracellular Ca2+ variation w ...
Centrin, an EF-hand calcium-binding protein, has been shown to be involved in the duplication of centrosomes, and Sfi1 (Suppressor of fermentation-induced loss of stress resistance protein 1) is one of its centrosomal targets. There are three isoforms of h ...
Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electron micrographs and X-ray crystallography of the components. Partial ...
Electron crystallography is a powerful technique for the structure determination of membrane proteins as well as soluble proteins. Sample preparation for 2D membrane protein crystals is a crucial step, as proteins have to be prepared for electron microscop ...
In this paper we present an electrical model of the inner hair cell based on an improved mathematical model. The model is implemented in silicon in the current domain using translinear circuits. It improves on previous models by taking into consideration t ...
The M2 protein of influenza A virus performs the crucial function of transporting protons to the interior of virions enclosed in the endosome. Adamantane drugs, amantadine (AMN) and rimantidine (RMN), block the proton conduction in some strains, and have b ...
Microporous limestones composed of micrite crystals constitute sizeable hydrocarbon reservoirs throughout the world and especially in the Middle East. However, the crystallization history of micrites is poorly understood. Scanning electronic microscopy (SE ...
The comparable order of magnitude between interatomic distances in a crystal and the wavelength of X-rays make X-ray crystallography the ideal analytical tool to gain insight into the structure of crystalline material, including biomolecules. Nevertheless, ...
CitS from Klebsiella pneumoniae acts as a secondary symporter of citrate and sodium ions across the inner membrane of the host. The protein is the best characterized member of the 2-hydroxycarboxylate transporter family, while no experimental structural in ...