Optimizing the trade-off between performance measures and operational risk in a food supply chain environment
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The effects of solar ultraviolet (UV) radiation on life on Earth differ greatly. While overexposure to UV rays is harmful, small amounts of exposure are necessary for the synthesis of Vitamin D and good health. To optimize individual exposure to solar UV, ...
Erectile dysfunction (ED) is a widespread disease affecting approximately 20% of men. With a rising incidence due to the global
ageing of the world population, it is estimated that over 322 million patients will be affected in 2025. While not being a lifet ...
Water has been foreseen to be the cause of the next great global crisis. India has 18% of the world population but only 4% of the world’s water resources. This brings us to the important issue that India may lack overall long-term availability of replenish ...
Paul Scherrer Institute, World Resources Forum2019
Access to healthcare is a requirement for human well-being that is constrained, in part, by the allocation of healthcare resources relative to the geographically dispersed human population(1-3). Quantifying access to care globally is challenging due to the ...
SARS-CoV2 spread is hard to control, as asymptomatic people contribute to transmission. Currently, Covid-19 mitigation imposes social distancing and isolates the diseased. This slows down virus spread, eases stress on health care systems and thereby reduce ...
Background: Understanding the association between motor capacity (MC) (what people can do in a standardized environment), mobility performance (MP) (what people actually do in real-life) and falls is important for early detection of and counteracting on fu ...
In this paper, we focus on the problem of minimizing a network of state facilities that provide essential public services (schools, offices, and hospitals). The goal is to reduce the size of the network in order to minimize the costs associated with it. Ho ...
The response of microbes to external signals is mediated by biochemical networks with intrinsic time scales. These time scales give rise to a memory that impacts cellular behaviour. Here we study theoretically the role of cellular memory in Escherichia col ...
The current manufacturing trend is towards sustainability. Due to the degradation of natural resources and the accumulation of waste with an increase in the world population and in the consumption of goods, many countries attempt to switch from a linear to ...
Post-translational modifications (PTMs) within the first 17 amino acids (Nt17) of the Huntingtin protein (Htt) have been shown to inhibit the aggregation and attenuate the toxicity of mutant Htt proteins in vitro and in various models of Huntington’s disea ...