MadagascarMadagascar, officially the Republic of Madagascar, is an island country lying off the southeastern coast of Africa. It is the world's fourth largest island, the second-largest island country and the 46th largest country in the world. Its capital and largest city is Antananarivo. Madagascar consists of an eponymous main island and numerous smaller peripheral islands.
History of Southeast AsiaThe history of Southeast Asia covers the people of Southeast Asia from prehistory to the present in two distinct sub-regions: Mainland Southeast Asia (or Indochina) and Maritime Southeast Asia (or Insular Southeast Asia). Mainland Southeast Asia comprises Cambodia, Laos, Myanmar (or Burma), Peninsular Malaysia, Thailand and Vietnam whereas Maritime Southeast Asia comprises Brunei, Cocos (Keeling) Islands, Christmas Island, East Malaysia, East Timor, Indonesia, Philippines and Singapore.
GenotypeThe genotype of an organism is its complete set of genetic material. Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. The number of alleles an individual can have in a specific gene depends on the number of copies of each chromosome found in that species, also referred to as ploidy. In diploid species like humans, two full sets of chromosomes are present, meaning each individual has two alleles for any given gene.
Human migrationHuman migration is the movement of people from one place to another with intentions of settling, permanently or temporarily, at a new location (geographic region). The movement often occurs over long distances and from one country to another (external migration), but internal migration (within a single country) is also possible; indeed, this is the dominant form of human migration globally. Migration is often associated with better human capital at both individual and household level, and with better access to migration networks, facilitating a possible second move.
History of the Middle EastThe Middle East, also known as the Near East, is home to one of the Cradles of Civilization and has seen many of the world's oldest cultures and civilizations. The region's history started from the earliest human settlements and continues through several major pre- and post-Islamic Empires to today's nation-states of the Middle East. The Sumerians became the first people to develop complex systems that were to be called "civilization" as far back as the 5th millennium BC.
Personal genomicsPersonal genomics or consumer genetics is the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different techniques, including single-nucleotide polymorphism (SNP) analysis chips (typically 0.02% of the genome), or partial or full genome sequencing. Once the genotypes are known, the individual's variations can be compared with the published literature to determine likelihood of trait expression, ancestry inference and disease risk.
Maritime Southeast AsiaMaritime Southeast Asia comprises the countries of Brunei, Indonesia, Malaysia, the Philippines, Singapore, and East Timor. The term Island Southeast Asia or Insular Southeast Asia is sometimes given the same meaning as Maritime Southeast Asia. Other definitions restrict Island Southeast Asia to just the islands between mainland Southeast Asia and the continental shelf of Australia and New Guinea. There is some variability as to whether Taiwan is included in this.
Early human migrationsEarly human migrations are the earliest migrations and expansions of archaic and modern humans across continents. They are believed to have begun approximately 2 million years ago with the early expansions out of Africa by Homo erectus. This initial migration was followed by other archaic humans including H. heidelbergensis, which lived around 500,000 years ago and was the likely ancestor of Denisovans and Neanderthals as well as modern humans. Early hominids had likely crossed land bridges that have now sunk.
Gene polymorphismA gene is said to be polymorphic if more than one allele occupies that gene's locus within a population. In addition to having more than one allele at a specific locus, each allele must also occur in the population at a rate of at least 1% to generally be considered polymorphic. Gene polymorphisms can occur in any region of the genome. The majority of polymorphisms are silent, meaning they do not alter the function or expression of a gene. Some polymorphisms are visible.
Mainland Southeast AsiaMainland Southeast Asia, also known as Indochina or the Indochinese Peninsula, is the continental portion of Southeast Asia. It lies east of the Indian subcontinent and south of Mainland China and is bordered by the Indian Ocean to the west and the Pacific Ocean to the east. It includes the countries of Cambodia, Laos, Myanmar, Thailand, Vietnam, and the State of Malaya of Malaysia. The term Indochina (originally Indo-China) was coined in the early nineteenth century, emphasizing the historical cultural influence of Indian and Chinese civilizations on the area.
