Publication

Integrating regional perfusion CT information to improve prediction of infarction after stroke

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Preserved Corticospinal Tract Revealed by Acute Perfusion Imaging Relates to Better Outcome After Thrombectomy in Stroke

Friedhelm Christoph Hummel, Philipp Johannes Koch

BACKGROUND:The indication for mechanical thrombectomy (MT) in stroke patients with large vessel occlusion has been constantly expanded over the past years. Despite remarkable treatment effects at the group level in clinical trials, many patients remain sev ...

Philadelphia2023

Torque teno virus (TTV) is considered to be an ubiquitous member of the commensal human blood virome commonly reported in mixed genotype co-infections. This study investigates the genomic diversity of TTV in blood samples from 816 febrile Tanzanian childre ...

MDPI2022

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One paramount challenge in multi-ion-sensing arises from ion interference that degrades the accuracy of sensor calibration. Machine learning models are here proposed to optimize such multivariate calibration. However, the acquisition of big experimental da ...

2021

Discrete-Choice Mining of Social Processes

Victor Kristof

Poor decisions and selfish behaviors give rise to seemingly intractable global problems, such as the lack of transparency in democratic processes, the spread of conspiracy theories, and the rise in greenhouse gas emissions. However, people are more predict ...

EPFL2021

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Comprehensive monitoring of performance is essential for swimmers and swimming coaches to optimize the training. Regardless of the swimming technique, the swimmer passes various swimming phases from wall to wall, including a dive into the water or wall pus ...

FRONTIERS MEDIA SA2021

Bayesian modeling of brain function and behavior

Maya Anna Jastrzebowska

The application of Bayesian modeling techniques is increasingly common in neuroscience due to the coherent and principled way in which the paradigm deals with uncertainty. The Bayesian framework is particularly valuable in the context of complex, ill-posed ...

EPFL2020

Automatic L2 Regularization for Multiple Generalized Additive Models

Yousra El Bachir

Multiple generalized additive models are a class of statistical regression models wherein parameters of probability distributions incorporate information through additive smooth functions of predictors. The functions are represented by basis function expan ...

EPFL2019

Learning without Smoothness and Strong Convexity

Yen-Huan Li

Recent advances in statistical learning and convex optimization have inspired many successful practices. Standard theories assume smoothness---bounded gradient, Hessian, etc.---and strong convexity of the loss function. Unfortunately, such conditions may ...

EPFL2018

Hypertonic Lactate to Improve Cerebral Perfusion and Glucose Availability After Acute Brain Injury

Pierre Magistretti, Jocelyne Bloch

Objectives: Lactate promotes cerebral blood flow and is an efficient substrate for the brain, particularly at times of glucose shortage. Hypertonic lactate is neuroprotective after experimental brain injury; however, human data are limited. Design: Prospec ...

LIPPINCOTT WILLIAMS & WILKINS2018

Structural and functional brain imaging using extended-focus optical coherence tomography and microscopy

Paul James Marchand

Neuroimaging techniques aim at revealing the anatomy and functional organisation of cerebral structures. Over the past decades, functional magnetic resonance imaging (fMRI) has revolutionized our understanding of human cerebral physiology through its abili ...

EPFL2018