The evolution of the type VI secretion system as a disintegration weapon
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Communication is fundamental to life on earth. All social organisms, from bacteria to humans, use communicative signals to coordinate their behaviors with members of their own and other species. Despite its key role in social organization, many questions r ...
A review with 15 refs. Directed mol. evolution of enzymes and proteins has emerged as an extremely powerful method to create proteins with novel properties, both for practical applications as well as for mechanistic studies. To demonstrate the underlying p ...
Numerous industries and facilities have been using chlorinated ethenes (CEs) as non-flammable solvents since the beginning of the 20th century. These compounds are known to persist in the environment, exerting adverse effects. They have been considered for ...
The past ten years of developmental genetics have revealed that most of our genes are shared by other species throughout the animal kingdom. Consequently, animal diversity might largely rely on the differential use of the same components, either at the ind ...
Co-evolution (i.e. the evolution of two or more competing populations with coupled fitness) has several interesting features that may potentially enhance the power of adaptation of artificial evolution. In particular, as discussed by Dawkins and Krebs [2], ...
Transcription factor binding site(s) (TFBS) gain and loss (i.e., turnover) is a well-documented feature of cis-regulatory module (CRM) evolution, yet little attention has been paid to the evolutionary force(s) driving this turnover process. The predominant ...
Numerous industries and facilities have been using chlorinated ethenes (CEs) as non-flammable solvents since the beginning of the 20th century. These compounds are known to persist in the environment, exerting adverse effects. They have been considered for ...
The present study examines the interaction of amine- and carboxyl- PEG core/shell quantum dots (QDs) with metal resistant bacterium Cupriavidus metallidurans CH34. The evolution of the number of QDs, their hydrodynamic radius, diffusion coefficients and si ...
Cytochrome c peroxidase (CCP) from Saccharomyces cerevisiae was subjected to directed mol. evolution to generate mutants with increased activity against the classical peroxidase substrate, guaiacol, thus changing the substrate specificity of CCP from the p ...
In the last few years several researchers have resorted to artificial evolution (e.g. genetic algorithms) and learning techniques (e.g. neural networks) for studying the interaction between learning and evolution. These studies have been conducted for two ...