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This contribution addresses the mathematical modeling and numerical approximation of the excitation-contraction coupling mechanisms in the heart. The main physiological issues are preliminarily sketched along with an extended overview to the relevant liter ...
Bio-equivalents (e.g., 17β-estradiol or dioxin equivalents) are commonly employed to quantify the in vitro effects of complex human or environmental samples. However, there is no generally accepted data analysis strategy for estimating and reporting bio-eq ...
Society of Environmental Toxicology and Chemistry Press2013
This project presents the theoretical background in electrophysiology that is used as a basis in the development of numerical methods for the simulation of heart’s electrical activity. We discuss the mathematical models currently used in cardiac electrophy ...
This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamen ...
We introduce an analysis framework for constructing optimal first-order primal-dual methods for the prototypical constrained convex optimization template. While this class of methods offers scalability advantages in obtaining numerical solutions, they have ...
In this paper we present a discontinuous Galerkin method applied to incompressible nonlinear elastostatics in a total Lagrangian deformation-pressure formulation, for which a suitable interior penalty stabilization is applied. We prove that the proposed di ...
We provide a mathematical analysis of and a numerical framework for full-field optical coherence elastography, which has unique features including micron-scale resolution, realtime processing, and noninvasive imaging. We develop a novel algorithm for trans ...
Society for Industrial and Applied Mathematics2015
We introduce and validate a novel mathematical model for computing the radial profiles of both axial and circumferential velocity components, respectively, of the swirling flow exiting the runner of hydraulic turbines within the full operating range. We as ...
In this paper, we show that tracking different kinds of interacting objects can be formulated as a network-flow Mixed Integer Program. This is made possible by tracking all objects simultaneously and expressing the fact that one object can appear or disapp ...
In the wide literature devoted to the cardiac structural mechanics, the strain energy proposed by Holzapfel and Ogden exhibits a number of interesting features: it has suitable mathematical properties and it is based on few material parameters that can, in ...