Publications related to Mitochondrial cristae modeled as an out-of-equilibrium membrane driven by a proton field

Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-L-S substrates

Sophisticated quality control mechanisms prolong retention of protein-folding intermediates in the endoplasmic reticulum (ER) until maturation while sorting out terminally misfolded polypeptides for ER-associated degradation (ERAD). The presence of structu ...

2010

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

Henning Paul-Julius Stahlberg

Two dynamin-related protein (DRP) families are essential for fusion of the outer and inner mitochondrial membranes, Fzo1 (yeast)/Mfn1/Mfn2 (mammals) and Mgm1 (yeast)/Opa1 (mammals), respectively. Fzo1/Mfns possess two medial transmembrane domains, which pl ...

Rockefeller University Press2009

Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells

Hui Wang

To explore the real-time dynamic behavior of molecular transporters of the cell-penetrating-peptide (CPP) type on a biological membrane, single fluorescently labeled oligoarginine conjugates were imaged interacting with the plasma membrane of Chinese hamst ...

2008

Spontaneous $ Na ^{ + } $ Transients in Individual Mitochondria of Intact Astrocytes

Michaël Unser, Dimitri Nestor Alice Van De Ville, Jean-Yves Chatton

Mitochondria in intact cells maintain low

Na ^{ + }

levels despite the large electrochemical gradient favoring cation influx into the matrix. In addition, they display individual spontaneous transient depolarizations. We report here that individual mit ...

Wiley-Liss2008

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

Giovanni D'Angelo

The phosphoinositides (PIs) are membrane phospholipids that actively operate at membrane-cytosol interfaces through the recruitment of a number of effector proteins. In this context, each of the seven different PI species represents a topological determina ...

2008

Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization

Françoise Gisou van der Goot Grunberg, Céline Lafourcade

The lumen of endosomal organelles becomes increasingly acidic when going from the cell surface to lysosomes. Luminal pH thereby regulates important processes such as the release of internalized ligands from their receptor or the activation of lysosomal enz ...

Public Library of Science2008

IMPROVED LARGE-AREA AND HIGH-DENSITY NANOSTENCIL LITHOGRAPHY

Jürgen Brugger, Marc Antonius Friedrich van den Boogaart

Patterning of micro- and nanometer scale structures by means of nanostencils (shadow masks) is increasingly being used as a simple, clean and low-cost alternative to photolithography. Currently, large area pattern transfer using nanostencil lithography is ...

2006

Some fundamental (and often overlooked) considerations underlying the free ion activity and biotic ligand models

Trace metal bioavailability is often evaluated on the basis of steady-state models such as the free ion activity model (FIAM) and the biotic ligand model (BLM). Some of the assumptions underlying these models were verified by examining Pb and Zn uptake by ...

2004

A method for introducing a nucleic acid into a eukaryotic cell

Florian Maria Wurm, Martin Jordan, Philippe Pierre Girard

Described is method for introducing a desired nucleic acid into a eukaryotic host cell, said method comprising a) admixing the desired nucleic acid, a mono- and/or divalent metal cation and a eukaryotic host cell lacking a cell wallb) incubating the mixtur ...

2003

Eukaryotic cells and microbial pathogens: a familiar couple take centre stage

Françoise Gisou van der Goot Grunberg

The interaction of a microbial pathogen with its host is a highly dynamic process shaped by evolution. Understanding cellular responses to microbial products is essential for a complete understanding of virulence. Similarly, studies aimed at determining ho ...

Nature Publishing Group2003

Mitochondrial cristae modeled as an out-of-equilibrium membrane driven by a proton field

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Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-L-S substrates

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells

Spontaneous $ Na ^{ + } $ Transients in Individual Mitochondria of Intact Astrocytes

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization

IMPROVED LARGE-AREA AND HIGH-DENSITY NANOSTENCIL LITHOGRAPHY

Some fundamental (and often overlooked) considerations underlying the free ion activity and biotic ligand models

A method for introducing a nucleic acid into a eukaryotic cell

Eukaryotic cells and microbial pathogens: a familiar couple take centre stage

Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells

Spontaneous $ Na ^{ + } $ Transients in Individual Mitochondria of Intact Astrocytes

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-L-S substrates

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

Some fundamental (and often overlooked) considerations underlying the free ion activity and biotic ligand models

IMPROVED LARGE-AREA AND HIGH-DENSITY NANOSTENCIL LITHOGRAPHY

Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization

A method for introducing a nucleic acid into a eukaryotic cell

Eukaryotic cells and microbial pathogens: a familiar couple take centre stage