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The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underl y-ing principles. As knowledge of cancer mechanisms has progressed, other facets of the dis ...
The present invention provides methods for detecting cancer as well as agents and compositions for treating cancer by modulating the expression and/or activity of one or more i) KRAB-containing zinc finger protein (KZFP), ii) mRNA encoding a KZFP, and/or i ...
In time-to-event settings, the presence of competing events complicates the definition of causal effects. Here we propose the new separable effects to study the causal effect of a treatment on an event of interest. The separable direct effect is the treatm ...
"I choose this restaurant because they have vegan sandwiches" could be a typical explanation we would expect from a human. However, current Reinforcement Learning (RL) techniques are not able to provide such explanations, when trained on raw pixels. RL alg ...
We revisit the problem of general identifiability originally introduced in [Lee et al., 2019] for causal inference and note that it is necessary to add positivity assumption of observational distribution to the original definition of the problem. We show t ...
Pearl's do calculus is a complete axiomatic approach to learn the identifiable causal effects from observational data. When such an effect is not identifiable, it is necessary to perform a collection of often costly interventions in the system to learn the ...
This paper analyzes efficiency and profitability in the Swiss banking sector over the period 1997–2019. We find strong evidence for scale economies: for most banks in the sample, efficiency and profitability increase with bank size. Using an instrumental v ...
This research explores the unreasoned influences of locational behaviour – i.e. locational habits – in Activity- Travel-Behaviour (ATB). In particular, the interrelations between Activity Space characteristics and mobility patterns. In a wider research eff ...
Observational studies reporting on adjusted associations between childhood body mass index (BMI; weight (kg)/height (m)(2)) rebound and subsequent cardiometabolic outcomes have often not paid explicit attention to causal inference, including definition of ...
We use quasi-random access to the Home Affordable Refinance Program (HARP) to identify the causal effect of refinancing into a lower-rate mortgage on borrower balance sheet outcomes. Refinancing substantially reduces borrower default rates on mortgages and ...