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The Mind Behind the Hebbian Synapse Donald O Hebb

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A history of spike-timing-dependent plasticity

Wulfram Gerstner, Henry Markram

How learning and memory is achieved in the brain is a central question in neuroscience. Key to today’s research into information storage in the brain is the concept of synaptic plasticity, a notion that has been heavily influenced by Hebb’s (1949) postulat ...

2011

Spike-timing dependent plasticity

Wulfram Gerstner

Spike Timing Dependent Plasticity (STDP) is a temporally asymmetric form of Hebbian learning induced by tight temporal correlations between the spikes of pre- and postsynaptic neurons. As with other forms of synaptic plasticity, it is widely believed that ...

2010

Rat model: neural substrates of the battered woman syndrome

Xavier Fontana

This study is part of a long term study on a male rat model of peripubertal stress in the Laboratory of Behavioural Genetics that shows increase aggressive behaviours against their partners. We are using here these rats in order to create a female rat mode ...

2010

Novelty of Behaviour as a Basis for the Neuro-evolution of Operant Reward Learning

Andrea Soltoggio

An agent that deviates from a usual or previous course of action can be said to display novel or varying behaviour. Novelty of behaviour can be seen as the result of real or apparent randomness in decision making, which prevents an agent from repeating exa ...

ACM2009

Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression

Wulfram Gerstner, Eleni Vasilaki, Claudia Clopath, Lorric Ziegler

Changes in synaptic efficacies need to be long-lasting in order to serve as a substrate for memory. Experimentally, synaptic plasticity exhibits phases covering the induction of long-term potentiation and depression (LTP/LTD) during the early phase of syna ...

Public Library of Science2008

Resonant neurons and bushcricket behaviour

Auke Ijspeert, Jonas Buchli

The resonant properties of the intrinsic dynamics of single neurons could play a direct role in behaviour. One plausible role is in the recognition of temporal patterns, such as that seen in the auditory communication systems of Orthoptera. Recent behaviou ...

2007

The role of the amygdala in emotional memories

Maria del Carmen Sandi Perez, Kamila Markram

This thesis investigates the role of the amygdala for the establishment of fear memories with a multidisciplinary approach, including behavioural, psychopharmacological, genetic, molecular, and electrophysiological techniques in rats or mice, under healthy ...

EPFL2007

Spatial learning and navigation in the rat

Ricardo Andres Chavarriaga Lozano

Animals behave in different ways depending on the specific task they are required to solve. In certain cases, if a cue marks the goal location, they can rely on simple stimulusresponse associations. In contrast, other tasks require the animal to be endowed ...

EPFL2005

An introduction to the constitutive modelling of unsaturated soils

Lyesse Laloui, Mathieu Nuth

An introduction to the constitutive modelling of unsaturated soils is presented. To facilitate understanding by the inexperienced reader, the paper considers the basic aspects of modelling of the behaviour of unsaturated soils from a qualitative point of v ...

2005

Competition between cue response and place response: A model of rat navigation behaviour

Wulfram Gerstner, Ricardo Andres Chavarriaga Lozano, Thomas Strösslin

Different neural systems are involved in animal navigation depending on the type of task. Experimental studies support the idea that the hippocampus is necessary to learn a spatial representation required to navigate toward hidden goals (place response), w ...

Taylor & Francis2005