Synchronous nonmonotonic changes in functional connectivity and white matter integrity in a rat model of sporadic Alzheimer's disease
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Growing evidence suggests that endogenous lactate is an important substrate for neurons. This study aimed to examine cerebral lactate metabolism and its relationship with brain perfusion in patients with severe traumatic brain injury (TBI). A prospective c ...
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Introduction: Medial Temporal Lobe Epilepsy (mTLE) with hippocampal sclerosis is the most frequent cause of drug-resistant focal epilepsy in adults. These patients suffer from widespread subtle white matter abnormalities and abnormal functional connectivit ...
Objective Lactoferrin (Lf) is an iron-binding glycoprotein secreted in maternal milk presenting anti-inflammatory and antioxidant properties. It shows efficient absorption into the brain from nutritional source. Brain injury frequently resulting from cereb ...
We review here the impact of early adversities on the development of violence and antisocial behaviour in humans, and present three etiological animal models of escalated rodent aggression, each disentangling the consequences of one particular adverse earl ...
The development of the human brain, from the fetal period until childhood, happens in a series of intertwined neurogenetical and histogenetical events that are influenced by environment. Neuronal proliferation and migration, cell aggregation, axonal ingrow ...
The development of the human brain, from the fetal period until childhood, happens in a series of inter- twined neurogenetical and histogenetical events that are influenced by environment. Neuronal proliferation and mi- gration, cell aggregation, axonal in ...
Lactate may represent a supplemental fuel for the brain. We examined cerebral lactate metabolism during prolonged brain glucose depletion (GD) in acute brain injury (ABI) patients monitored with cerebral microdialysis (CMD). Sixty episodes of GD (defined a ...
Human brain is organized by a large number of functionally correlated but spatially distributed cortical neurons. Cognitive processes are usually associated with dynamic interactions among multiple brain regions. Therefore, the understanding of brain funct ...