ProteasomeProteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that help such reactions are called proteases. Proteasomes are part of a major mechanism by which cells regulate the concentration of particular proteins and degrade misfolded proteins. Proteins are tagged for degradation with a small protein called ubiquitin. The tagging reaction is catalyzed by enzymes called ubiquitin ligases.
Chaperone (protein)In molecular biology, molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein complexes. There are a number of classes of molecular chaperones, all of which function to assist large proteins in proper protein folding during or after synthesis, and after partial denaturation. Chaperones are also involved in the translocation of proteins for proteolysis. The first molecular chaperones discovered were a type of assembly chaperones which assist in the assembly of nucleosomes from folded histones and DNA.
Publicly funded health carePublicly funded healthcare is a form of health care financing designed to meet the cost of all or most healthcare needs from a publicly managed fund. Usually this is under some form of democratic accountability, the right of access to which are set down in rules applying to the whole population contributing to the fund or receiving benefits from it. The fund may be a not-for-profit trust that pays out for healthcare according to common rules established by the members or by some other democratic form.
Intensive pig farmingIntensive pig farming, also known as pig factory farming, is the primary method of pig production, in which grower pigs are housed indoors in group-housing or straw-lined sheds, whilst pregnant sows are housed in gestation crates or pens and give birth in farrowing crates. The use of gestation crates for pregnant sows has lowered birth production costs; Gestation crates or individual stalls are used as a way to nurture the animals and protect them first during pregnancy.
Medicine in the medieval Islamic worldIn the history of medicine, "Islamic medicine" is the science of medicine developed in the Middle East, and usually written in Arabic, the lingua franca of Islamic civilization. Islamic medicine adopted, systematized and developed the medical knowledge of classical antiquity, including the major traditions of Hippocrates, Galen and Dioscorides. During the post-classical era, Middle Eastern medicine was the most advanced in the world, integrating concepts of ancient Greek, Roman, Mesopotamian and Persian medicine as well as the ancient Indian tradition of Ayurveda, while making numerous advances and innovations.
Pervasive developmental disorderThe diagnostic category pervasive developmental disorders (PDD), as opposed to specific developmental disorders (SDD), was a group of disorders characterized by delays in the development of multiple basic functions including socialization and communication. It was defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM) (from 1980 to 2013), and the International Classification of Diseases (ICD) (until 2022).
Socialized medicineSocialized medicine is a term used in the United States to describe and discuss systems of universal health care—medical and hospital care for all by means of government regulation of health care and subsidies derived from taxation. Because of historically negative associations with socialism in American culture, the term is usually used pejoratively in American political discourse. The term was first widely used in the United States by advocates of the American Medical Association in opposition to President Harry S.
