Automated Analysis of Cerebrospinal Fluid Flow and Motile Cilia Properties in The Central Canal of Zebrafish Embryos
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Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by the selective and gradual loss of motoneurons in the brain and spinal cord. A persistent inflammation, typified by the activation of astrocytes and microglia, ...
Cerebrospinal fluid (CSF) dynamics in the spinal subarachnoid space (SSS) have been thought to play an important pathophysiological role in syringomyelia, Chiari I malformation (CM), and a role in intrathecal drug delivery. Yet, the impact that fine anatom ...
Cerebrospinal fluid (CSF) dynamics in the cervical spinal subarachnoid space (SSS) have been thought to be important to help diagnose and assess craniospinal disorders such as Chiari I malformation (CM). In this study we obtained time-resolved three direct ...
Public Library Science2012
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The development of novel therapies against neurodegenerative disorders requires the ability to detect their early, presymptomatic manifestations in order to enable treatment before irreversible cellular damage occurs. Precocious signs indicative of neurode ...
Amer Soc Biochemistry Molecular Biology Inc2013
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Martin BA, Reymond P, Novy J, Baledent O, Stergiopulos N. A coupled hydrodynamic model of the cardiovascular and cerebrospinal fluid system. Am J Physiol Heart Circ Physiol 302: H1492-H1509, 2012. First published January 20, 2012; doi: 10.1152/ajpheart.006 ...
The driving force that causes enlargement of the ventricles remains unclear in case of normal pressure hydrocephalus (NPH). Both healthy and NPH brain conditions are characterized by a low transparenchymal pressure drop, typically 1 mm Hg. The present pape ...
Ferritin H, the major iron storage protein, has essential functions in early embryonic development as well as in adult liver and intestine. To address the question whether ferritin H has similarly essential functions in the brain we used the Cre/loxP syste ...
Network industries, such as electricity, railways and air transport, are very complex technical, economic, and political systems in which the alignment between technology and institutions has a significant impact on performance. This alignment has been stu ...
Social media platforms are created and exploited for various activities carried out individually or collaboratively and relying on different resources and tools. Social media platforms are inherently contextual; the context being defined as a specific acti ...
This paper aims at giving a definition for waste heat in analogy to the definitions of natural resources and reserves. It aims also at presenting a method for identifying, characterizing and quantifying the available waste heat of an industrial system that ...
Czech Society of Chemical Engineering and Italian Association of Chemical Engineering2012