Time-Resolved Transmission Electron Microscopy: Instrumentation and Applications
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Life sciences have a constantly growing need for novel methodological approaches suitable to investigate the intracellular environment with increased temporal and spatial resolutions. Recently, optical near-field probes, such as laser-irradiated pointed me ...
Carbon nanotubes with unique physical and mechanical properties have shown great potential for biological applications, including tissue engineering and mimicking the structure and properties of human bones. In the present work, sol-gel synthesized nanocom ...
The localized growth of carbon nanotube structures has potential in many applications such as interconnects, field emitters and sensors. Using a laser to locally heat the substrate offers a highly versatile process compatible with a broad range of substrat ...
The ability to reshape nanopores and observe their shrinkage under an electron microscope is a powerful and novel technique. It increases the sensitivity of the resistive pulse sensing and enables to detect very short and small molecules. However, this has ...
This device is for holding samples during their preparation prior to imaging in the electron microscope. The design means it can be transferred between the light and electron microscopes as well as trimming devices used to prepare the final sample. It can ...
Energy-filtered transmission electron microscopy images are acquired during the reduction of a NiO-YSZ composite in H-2 up to 600 degrees C. Temperature-resolved quantitative information about both chemistry and structure is extracted with nm spatial resol ...
Loss of T-tubules (TT), sarcolemmal invaginations of cardiomyocytes (CMs), was recently identified as a general heart failure (HF) hallmark. However, whether IT per se or the overall sarcolemma is altered during HF process is still unknown. In this study, ...
A new type of monochromator has been developed for energy-selective neutron imaging at continuous sources. It combines the use of a mechanical neutron velocity selector with pyrolytic graphite crystals of different mosaicity. The beam can be monochromatize ...
To produce short X-ray pulses for SwissFEL(1), it is necessary to compress the electron bunches by a factor of 300, down to sub-fs for the attosecond operational modes. To achieve stable EEL output accurate timing of the initial electron injection at the m ...
Correlating in vivo imaging of neurons and their synaptic connections with electron microscopy combines dynamic and ultrastructural information. Here we describe a semi-automated technique whereby volumes of brain tissue containing axons and dendrites, pre ...